node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
araA | araB | b0062 | b0063 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | 0.999 |
araA | araC | b0062 | b0064 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | Ara regulon transcriptional activator; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. Functions both as a positive and a negative regulator. In the presence of arabinose, activates the expression of the araBAD, araE, araFGH and araJ promoters. In the absence of arabinose, negatively regulates the araBAD operon. Represses its own transcription. Acts by binding directly to DNA. | 0.824 |
araA | araD | b0062 | b0061 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D- xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon- carbon bond cleavage analogous to a class II aldolase reaction). | 0.999 |
araA | araE | b0062 | b2841 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | Arabinose transporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system). | 0.936 |
araA | araF | b0062 | b1901 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | L-arabinose ABC transporter periplasmic binding protein; Involved in the high-affinity L-arabinose membrane transport system. Binds with high affinity to arabinose, but can also bind D- galactose (approximately 2-fold reduction) and D-fucose (approximately 40-fold reduction). | 0.447 |
araA | xylA | b0062 | b3565 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | D-xylose isomerase; Protein involved in carbohydrate catabolic process and glucose metabolic process; Belongs to the xylose isomerase family. | 0.936 |
araA | xylB | b0062 | b3564 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | Xylulokinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate. Also catalyzes the phosphorylation of 1- deoxy-D-xylulose to 1-deoxy-D-xylulose 5-phosphate, with lower efficiency. Can also use D-ribulose, xylitol and D- arabitol, but D-xylulose is preferred over the other substrates. Has a weak substrate-independent Mg-ATP-hydrolyzing activity ; Belongs to the FGGY kinase family. | 0.837 |
araB | araA | b0063 | b0062 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | 0.999 |
araB | araC | b0063 | b0064 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | Ara regulon transcriptional activator; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. Functions both as a positive and a negative regulator. In the presence of arabinose, activates the expression of the araBAD, araE, araFGH and araJ promoters. In the absence of arabinose, negatively regulates the araBAD operon. Represses its own transcription. Acts by binding directly to DNA. | 0.932 |
araB | araD | b0063 | b0061 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D- xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon- carbon bond cleavage analogous to a class II aldolase reaction). | 0.999 |
araB | araE | b0063 | b2841 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | Arabinose transporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system). | 0.958 |
araB | araF | b0063 | b1901 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | L-arabinose ABC transporter periplasmic binding protein; Involved in the high-affinity L-arabinose membrane transport system. Binds with high affinity to arabinose, but can also bind D- galactose (approximately 2-fold reduction) and D-fucose (approximately 40-fold reduction). | 0.638 |
araB | xylA | b0063 | b3565 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | D-xylose isomerase; Protein involved in carbohydrate catabolic process and glucose metabolic process; Belongs to the xylose isomerase family. | 0.927 |
araB | xylB | b0063 | b3564 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | Xylulokinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate. Also catalyzes the phosphorylation of 1- deoxy-D-xylulose to 1-deoxy-D-xylulose 5-phosphate, with lower efficiency. Can also use D-ribulose, xylitol and D- arabitol, but D-xylulose is preferred over the other substrates. Has a weak substrate-independent Mg-ATP-hydrolyzing activity ; Belongs to the FGGY kinase family. | 0.846 |
araC | araA | b0064 | b0062 | Ara regulon transcriptional activator; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. Functions both as a positive and a negative regulator. In the presence of arabinose, activates the expression of the araBAD, araE, araFGH and araJ promoters. In the absence of arabinose, negatively regulates the araBAD operon. Represses its own transcription. Acts by binding directly to DNA. | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | 0.824 |
araC | araB | b0064 | b0063 | Ara regulon transcriptional activator; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. Functions both as a positive and a negative regulator. In the presence of arabinose, activates the expression of the araBAD, araE, araFGH and araJ promoters. In the absence of arabinose, negatively regulates the araBAD operon. Represses its own transcription. Acts by binding directly to DNA. | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | 0.932 |
araC | araD | b0064 | b0061 | Ara regulon transcriptional activator; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. Functions both as a positive and a negative regulator. In the presence of arabinose, activates the expression of the araBAD, araE, araFGH and araJ promoters. In the absence of arabinose, negatively regulates the araBAD operon. Represses its own transcription. Acts by binding directly to DNA. | L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D- xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon- carbon bond cleavage analogous to a class II aldolase reaction). | 0.715 |
araC | araE | b0064 | b2841 | Ara regulon transcriptional activator; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. Functions both as a positive and a negative regulator. In the presence of arabinose, activates the expression of the araBAD, araE, araFGH and araJ promoters. In the absence of arabinose, negatively regulates the araBAD operon. Represses its own transcription. Acts by binding directly to DNA. | Arabinose transporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system). | 0.877 |
araC | araF | b0064 | b1901 | Ara regulon transcriptional activator; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. Functions both as a positive and a negative regulator. In the presence of arabinose, activates the expression of the araBAD, araE, araFGH and araJ promoters. In the absence of arabinose, negatively regulates the araBAD operon. Represses its own transcription. Acts by binding directly to DNA. | L-arabinose ABC transporter periplasmic binding protein; Involved in the high-affinity L-arabinose membrane transport system. Binds with high affinity to arabinose, but can also bind D- galactose (approximately 2-fold reduction) and D-fucose (approximately 40-fold reduction). | 0.750 |
araC | araJ | b0064 | b0396 | Ara regulon transcriptional activator; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. Functions both as a positive and a negative regulator. In the presence of arabinose, activates the expression of the araBAD, araE, araFGH and araJ promoters. In the absence of arabinose, negatively regulates the araBAD operon. Represses its own transcription. Acts by binding directly to DNA. | L-arabinose-inducible putative transporter, MFS family; May be involved in either the transport or processing of arabinose polymers; Belongs to the major facilitator superfamily. | 0.621 |