STRINGSTRING
aslB aslB yidF yidF aslA aslA ydeN ydeN yidJ yidJ bioB bioB yifB yifB pqqL pqqL epmB epmB accA accA lipA lipA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aslBPutative AslA-specific sulfatase-maturating enzyme; Putative arylsulfatase regulator; Protein involved in sulfur metabolic process and protein folding; Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. (411 aa)    
Predicted Functional Partners:
yidF
Putative Cys-type oxidative YidJ-maturating enzyme; Putative transcriptional regulator.
  
   
 0.977
aslA
Putative Ser-type periplasmic non-aryl sulfatase; No E.coli strains have been observed to have an arylsulfatase activity. A 'latent' activity has been observed by heterologous expression of a genomic region linked to tynA, but it does not map near aslA; Belongs to the sulfatase family.
 
 
 0.958
ydeN
Putative Ser-type periplasmic non-aryl sulfatase; Putative sulfatase; Protein involved in sulfur metabolic process; Belongs to the sulfatase family.
 
 
   0.792
yidJ
Sulfatase/phosphatase superfamily protein; Putative sulfatase; Protein involved in sulfur metabolic process; Belongs to the sulfatase family.
 
   0.752
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
      
 0.731
yifB
Magnesium chelatase family protein and putative transcriptional regulator; Putative 2-component regulator; Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.
   
  
 0.585
pqqL
Putative periplasmic M16 family zinc metalloendopeptidase; Putative zinc protease.
     
 0.532
epmB
EF-P-Lys34 lysylation protein; With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. EpmB appears to act before EpmA. Displays lysine 2,3- aminomutase activity, producing (R)-beta-lysine from (S)-alpha-lysine (L-lysine). Cannot use (S)-ornithine or (R)-alpha-lysine as a substrate; Belongs to the radical SAM superfamily. KamA family.
   
  
 0.529
accA
acetyl-CoA carboxylase, carboxytransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. Belongs to the AccA family.
      
 0.518
lipA
Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. Free octanoate is not a substrate for LipA; Belongs to the radical SAM superfamily. Lipoyl synthase family.
      
 0.452
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.