node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acrZ | yjcB | b0762 | b4060 | AcrAB-TolC efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export. | Putative inner membrane protein. | 0.483 |
alaE | yjcB | b2670 | b4060 | Alanine exporter, alanine-inducible, stress-responsive; Exports L-alanine; Belongs to the AlaE exporter family. | Putative inner membrane protein. | 0.594 |
ligT | yjcB | b0147 | b4060 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester. In vitro, can also ligate 5' and 3' half-tRNA molecules with 2',3'-cyclic phosphate and 5'-hydroxyl termini, respectively, to the product containing the 2'-5' phosphodiester linkage. This reaction does not require ATP and is reversible. Belongs to the 2H phosphoesterase superfamily. ThpR family. | Putative inner membrane protein. | 0.532 |
ybaO | yjcB | b0447 | b4060 | Putative DNA-binding transcriptional regulator; Plays a role in L-cysteine detoxification. Binds to the dlsT(yhaO)-yhaM operon promoter in the presence but not absence of L- cysteine; activates transcription from the dlsT(yhaO)-yhaM operon. No other DNA target was identified in strain K12 / BW25113. Thiosulfate does not activate its transcription function. Overexpression doubles hydrogen sulfide production in the presence of cysteine. | Putative inner membrane protein. | 0.636 |
ybaO | ypeC | b0447 | b2390 | Putative DNA-binding transcriptional regulator; Plays a role in L-cysteine detoxification. Binds to the dlsT(yhaO)-yhaM operon promoter in the presence but not absence of L- cysteine; activates transcription from the dlsT(yhaO)-yhaM operon. No other DNA target was identified in strain K12 / BW25113. Thiosulfate does not activate its transcription function. Overexpression doubles hydrogen sulfide production in the presence of cysteine. | DUF2502 family putative periplasmic protein; The overlapping reading frame (b2391) is no longer thought to be an actual gene, and has been deaccessioned; To E.coli YaaX. | 0.522 |
ybjC | yjcB | b0850 | b4060 | DUF1418 family protein. | Putative inner membrane protein. | 0.526 |
ybjC | ypeC | b0850 | b2390 | DUF1418 family protein. | DUF2502 family putative periplasmic protein; The overlapping reading frame (b2391) is no longer thought to be an actual gene, and has been deaccessioned; To E.coli YaaX. | 0.519 |
ycgZ | yjcB | b1164 | b4060 | RcsB connector protein for regulation of biofilm and acid-resistance; Probably a connector protein for RcsB/C regulation of biofilm formation, providing additional signal input into the two-component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component. | Putative inner membrane protein. | 0.517 |
ycgZ | ypeC | b1164 | b2390 | RcsB connector protein for regulation of biofilm and acid-resistance; Probably a connector protein for RcsB/C regulation of biofilm formation, providing additional signal input into the two-component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component. | DUF2502 family putative periplasmic protein; The overlapping reading frame (b2391) is no longer thought to be an actual gene, and has been deaccessioned; To E.coli YaaX. | 0.502 |
yjcB | acrZ | b4060 | b0762 | Putative inner membrane protein. | AcrAB-TolC efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export. | 0.483 |
yjcB | alaE | b4060 | b2670 | Putative inner membrane protein. | Alanine exporter, alanine-inducible, stress-responsive; Exports L-alanine; Belongs to the AlaE exporter family. | 0.594 |
yjcB | ligT | b4060 | b0147 | Putative inner membrane protein. | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester. In vitro, can also ligate 5' and 3' half-tRNA molecules with 2',3'-cyclic phosphate and 5'-hydroxyl termini, respectively, to the product containing the 2'-5' phosphodiester linkage. This reaction does not require ATP and is reversible. Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.532 |
yjcB | ybaO | b4060 | b0447 | Putative inner membrane protein. | Putative DNA-binding transcriptional regulator; Plays a role in L-cysteine detoxification. Binds to the dlsT(yhaO)-yhaM operon promoter in the presence but not absence of L- cysteine; activates transcription from the dlsT(yhaO)-yhaM operon. No other DNA target was identified in strain K12 / BW25113. Thiosulfate does not activate its transcription function. Overexpression doubles hydrogen sulfide production in the presence of cysteine. | 0.636 |
yjcB | ybjC | b4060 | b0850 | Putative inner membrane protein. | DUF1418 family protein. | 0.526 |
yjcB | ycgZ | b4060 | b1164 | Putative inner membrane protein. | RcsB connector protein for regulation of biofilm and acid-resistance; Probably a connector protein for RcsB/C regulation of biofilm formation, providing additional signal input into the two-component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component. | 0.517 |
yjcB | yohC | b4060 | b2135 | Putative inner membrane protein. | Yip1 family inner membrane protein. | 0.652 |
yjcB | ypeC | b4060 | b2390 | Putative inner membrane protein. | DUF2502 family putative periplasmic protein; The overlapping reading frame (b2391) is no longer thought to be an actual gene, and has been deaccessioned; To E.coli YaaX. | 0.811 |
yohC | yjcB | b2135 | b4060 | Yip1 family inner membrane protein. | Putative inner membrane protein. | 0.652 |
ypeC | ybaO | b2390 | b0447 | DUF2502 family putative periplasmic protein; The overlapping reading frame (b2391) is no longer thought to be an actual gene, and has been deaccessioned; To E.coli YaaX. | Putative DNA-binding transcriptional regulator; Plays a role in L-cysteine detoxification. Binds to the dlsT(yhaO)-yhaM operon promoter in the presence but not absence of L- cysteine; activates transcription from the dlsT(yhaO)-yhaM operon. No other DNA target was identified in strain K12 / BW25113. Thiosulfate does not activate its transcription function. Overexpression doubles hydrogen sulfide production in the presence of cysteine. | 0.522 |
ypeC | ybjC | b2390 | b0850 | DUF2502 family putative periplasmic protein; The overlapping reading frame (b2391) is no longer thought to be an actual gene, and has been deaccessioned; To E.coli YaaX. | DUF1418 family protein. | 0.519 |