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Mpal_1572 Mpal_1572 ndk ndk Mpal_1867 Mpal_1867 Mpal_0009 Mpal_0009 Mpal_0729 Mpal_0729 moaA moaA mptA mptA Mpal_1571 Mpal_1571 Mpal_2511 Mpal_2511 mat mat dacZ-2 dacZ-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Mpal_1572TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: mbn:Mboo_1326 putative adenylyl cyclase CyaB. (175 aa)    
Predicted Functional Partners:
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
  0.902
Mpal_1867
KEGG: mem:Memar_0527 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
    
  0.901
Mpal_0009
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: mem:Memar_0320 anaerobic ribonucleoside-triphosphate reductase.
     
  0.900
Mpal_0729
KEGG: mem:Memar_0034 nucleotide kinase-like protein.
     
  0.900
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
    
  0.817
mptA
Protein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
    
  0.802
Mpal_1571
PFAM: peptidylprolyl isomerase FKBP-type; KEGG: mem:Memar_0935 peptidylprolyl isomerase, FKBP-type.
       0.707
Mpal_2511
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mem:Memar_2360 helix-turn-helix domain-containing protein.
 
     0.540
mat
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family.
 
     0.536
dacZ-2
Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
 
   
 0.536
Your Current Organism:
Methanosphaerula palustris
NCBI taxonomy Id: 521011
Other names: Candidatus Methanosphaerula palustris E1-9c, M. palustris E1-9c, Methanosphaerula palustris E1-9c, Methanosphaerula palustris str. E1-9c, Methanosphaerula palustris strain E1-9c
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