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gpr gpr spoVAD-2 spoVAD-2 spoVAD spoVAD spoVAC-2 spoVAC-2 spoVAC spoVAC spoIIP-2 spoIIP-2 spoIVB spoIVB spoIVA spoIVA spoIIP spoIIP spo0A spo0A spoIIAB spoIIAB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
gprSpore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination. (370 aa)    
Predicted Functional Partners:
spoVAD-2
Stage V sporulation protein AD.
  
  
 0.882
spoVAD
Stage V sporulation protein AD.
  
  
 0.879
spoVAC-2
Stage V sporulation protein AC.
  
  
 0.845
spoVAC
Stage V sporulation protein AC.
  
  
 0.838
spoIIP-2
Stage II sporulation protein P.
 
  
 0.824
spoIVB
Stage IV sporulation protein B.
  
    0.822
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.816
spoIIP
Stage II sporulation protein P.
 
  
 0.811
spo0A
Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.802
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.792
Your Current Organism:
Bacillus megaterium QM B1551
NCBI taxonomy Id: 545693
Other names: B. megaterium QM B1551, Bacillus megaterium str. QM B1551, Bacillus megaterium strain QM B1551
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