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kgd kgd lpdA1 lpdA1 sucB sucB lpdA2 lpdA2 LHK_01492 LHK_01492 sucC sucC LHK_02269 LHK_02269 aceF aceF icd1 icd1 LHK_02342 LHK_02342 sdhC sdhC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
kgdKgd; 2-oxoglutarate dehydrogenase E1 component. (939 aa)    
Predicted Functional Partners:
lpdA1
LpdA1; Dihydrolipoamide dehydrogenase.
 
 0.999
sucB
SucB; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.999
lpdA2
LpdA2; Dihydrolipoyl dehydrogenase.
 
 0.995
LHK_01492
Probable dihydrolipoamide dehydrogenase.
  
 0.989
sucC
SucC; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.988
LHK_02269
Catalytic domain of components of various dehydrogenase complexes.
 
 0.979
aceF
AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.978
icd1
Icd1; Isocitrate dehydrogenase.
   
 
 0.976
LHK_02342
Succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 
 0.928
sdhC
SdhC; Succinate dehydrogenase cytochrome b-556 subunit.
  
  
 0.922
Your Current Organism:
Laribacter hongkongensis
NCBI taxonomy Id: 557598
Other names: L. hongkongensis HLHK9, Laribacter hongkongensis HLHK9, Laribacter hongkongensis str. HLHK9, Laribacter hongkongensis strain HLHK9
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