node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PC1_0448 | PC1_1083 | PC1_0448 | PC1_1083 | Transcriptional regulator, XRE family; KEGG: eca:ECA0463 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: eca:ECA1184 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Belongs to the 5'-nucleotidase family. | 0.916 |
PC1_0448 | PC1_1968 | PC1_0448 | PC1_1968 | Transcriptional regulator, XRE family; KEGG: eca:ECA0463 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. | Nicotinamidase; PFAM: isochorismatase hydrolase; KEGG: eca:ECA2341 nicotinamidase/pyrazinamidase. | 0.463 |
PC1_0448 | PC1_3214 | PC1_0448 | PC1_3214 | Transcriptional regulator, XRE family; KEGG: eca:ECA0463 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. | PFAM: CinA domain protein; KEGG: eca:ECA3370 competence damage-inducible protein A; Belongs to the CinA family. | 0.944 |
PC1_0448 | PC1_3388 | PC1_0448 | PC1_3388 | Transcriptional regulator, XRE family; KEGG: eca:ECA0463 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: eca:ECA3568 nucleoside triphosphate pyrophosphohydrolase. | 0.906 |
PC1_0448 | PC1_3574 | PC1_0448 | PC1_3574 | Transcriptional regulator, XRE family; KEGG: eca:ECA0463 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. | Nicotinate-nucleotide pyrophosphorylase; KEGG: eca:ECA3797 quinolinate phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | 0.936 |
PC1_0448 | PC1_3893 | PC1_0448 | PC1_3893 | Transcriptional regulator, XRE family; KEGG: eca:ECA0463 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: eca:ECA4103 putative hydrolase. | 0.911 |
PC1_0448 | deoD | PC1_0448 | PC1_0602 | Transcriptional regulator, XRE family; KEGG: eca:ECA0463 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. | TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: eca:ECA0730 purine nucleoside phosphorylase. | 0.919 |
PC1_0448 | nadD | PC1_0448 | PC1_1184 | Transcriptional regulator, XRE family; KEGG: eca:ECA0463 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.936 |
PC1_0448 | nudC | PC1_0448 | PC1_0218 | Transcriptional regulator, XRE family; KEGG: eca:ECA0463 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. | NAD(+) diphosphatase; PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase; KEGG: eca:ECA0234 NADH pyrophosphatase. | 0.903 |
PC1_0448 | pncB | PC1_0448 | PC1_1786 | Transcriptional regulator, XRE family; KEGG: eca:ECA0463 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.946 |
PC1_1083 | PC1_0448 | PC1_1083 | PC1_0448 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: eca:ECA1184 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Belongs to the 5'-nucleotidase family. | Transcriptional regulator, XRE family; KEGG: eca:ECA0463 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. | 0.916 |
PC1_1083 | PC1_3214 | PC1_1083 | PC1_3214 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: eca:ECA1184 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Belongs to the 5'-nucleotidase family. | PFAM: CinA domain protein; KEGG: eca:ECA3370 competence damage-inducible protein A; Belongs to the CinA family. | 0.903 |
PC1_1083 | PC1_3388 | PC1_1083 | PC1_3388 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: eca:ECA1184 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Belongs to the 5'-nucleotidase family. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: eca:ECA3568 nucleoside triphosphate pyrophosphohydrolase. | 0.903 |
PC1_1083 | PC1_3574 | PC1_1083 | PC1_3574 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: eca:ECA1184 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Belongs to the 5'-nucleotidase family. | Nicotinate-nucleotide pyrophosphorylase; KEGG: eca:ECA3797 quinolinate phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | 0.900 |
PC1_1083 | PC1_3893 | PC1_1083 | PC1_3893 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: eca:ECA1184 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Belongs to the 5'-nucleotidase family. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: eca:ECA4103 putative hydrolase. | 0.901 |
PC1_1083 | deoD | PC1_1083 | PC1_0602 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: eca:ECA1184 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Belongs to the 5'-nucleotidase family. | TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: eca:ECA0730 purine nucleoside phosphorylase. | 0.914 |
PC1_1083 | nadD | PC1_1083 | PC1_1184 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: eca:ECA1184 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Belongs to the 5'-nucleotidase family. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.900 |
PC1_1083 | nudC | PC1_1083 | PC1_0218 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: eca:ECA1184 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Belongs to the 5'-nucleotidase family. | NAD(+) diphosphatase; PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase; KEGG: eca:ECA0234 NADH pyrophosphatase. | 0.905 |
PC1_1083 | pncB | PC1_1083 | PC1_1786 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: eca:ECA1184 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Belongs to the 5'-nucleotidase family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.904 |
PC1_1968 | PC1_0448 | PC1_1968 | PC1_0448 | Nicotinamidase; PFAM: isochorismatase hydrolase; KEGG: eca:ECA2341 nicotinamidase/pyrazinamidase. | Transcriptional regulator, XRE family; KEGG: eca:ECA0463 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. | 0.463 |