node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argS | glnS | HDEF_0639 | HDEF_0764 | Arginine tRNA synthetase; COG0018. | Glutamine tRNA synthetase; COG0008. | 0.775 |
argS | gltX | HDEF_0639 | HDEF_0366 | Arginine tRNA synthetase; COG0018. | Glutamate tRNA synthetase, catalytic subunit; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 0.817 |
argS | ileS | HDEF_0639 | HDEF_0831 | Arginine tRNA synthetase; COG0018. | Isoleucine tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.917 |
argS | leuS | HDEF_0639 | HDEF_2038 | Arginine tRNA synthetase; COG0018. | Leucine tRNA synthetase; COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.876 |
argS | metG | HDEF_0639 | HDEF_1807 | Arginine tRNA synthetase; COG0018. | Methionine tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.877 |
argS | pheT | HDEF_0639 | HDEF_1830 | Arginine tRNA synthetase; COG0018. | Phenylalanine tRNA synthetase, beta-subunit; COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.870 |
argS | thrS | HDEF_0639 | HDEF_1824 | Arginine tRNA synthetase; COG0018. | Threonine tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | 0.656 |
argS | valS | HDEF_0639 | HDEF_0219 | Arginine tRNA synthetase; COG0018. | Valine tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.715 |
glnS | argS | HDEF_0764 | HDEF_0639 | Glutamine tRNA synthetase; COG0008. | Arginine tRNA synthetase; COG0018. | 0.775 |
glnS | gltX | HDEF_0764 | HDEF_0366 | Glutamine tRNA synthetase; COG0008. | Glutamate tRNA synthetase, catalytic subunit; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 0.490 |
glnS | ileS | HDEF_0764 | HDEF_0831 | Glutamine tRNA synthetase; COG0008. | Isoleucine tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.934 |
glnS | leuS | HDEF_0764 | HDEF_2038 | Glutamine tRNA synthetase; COG0008. | Leucine tRNA synthetase; COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.904 |
glnS | metG | HDEF_0764 | HDEF_1807 | Glutamine tRNA synthetase; COG0008. | Methionine tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.740 |
glnS | pheT | HDEF_0764 | HDEF_1830 | Glutamine tRNA synthetase; COG0008. | Phenylalanine tRNA synthetase, beta-subunit; COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.788 |
glnS | thrS | HDEF_0764 | HDEF_1824 | Glutamine tRNA synthetase; COG0008. | Threonine tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | 0.417 |
glnS | valS | HDEF_0764 | HDEF_0219 | Glutamine tRNA synthetase; COG0008. | Valine tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.510 |
gltX | argS | HDEF_0366 | HDEF_0639 | Glutamate tRNA synthetase, catalytic subunit; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Arginine tRNA synthetase; COG0018. | 0.817 |
gltX | glnS | HDEF_0366 | HDEF_0764 | Glutamate tRNA synthetase, catalytic subunit; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Glutamine tRNA synthetase; COG0008. | 0.490 |
gltX | ileS | HDEF_0366 | HDEF_0831 | Glutamate tRNA synthetase, catalytic subunit; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Isoleucine tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.892 |
gltX | leuS | HDEF_0366 | HDEF_2038 | Glutamate tRNA synthetase, catalytic subunit; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Leucine tRNA synthetase; COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.868 |