node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
purB | purC | ECUMN_1375 | ECUMN_2789 | Adenylosuccinate lyase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the SAICAR synthetase family. | 0.994 |
purB | purD | ECUMN_1375 | ECUMN_4529 | Adenylosuccinate lyase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide synthetase phosphoribosylamine-glycine ligase; Function experimentally demonstrated in the studied species; enzyme. | 0.944 |
purB | purE | ECUMN_1375 | ECUMN_0563 | Adenylosuccinate lyase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.907 |
purB | purF | ECUMN_1375 | ECUMN_2652 | Adenylosuccinate lyase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.965 |
purB | purH | ECUMN_1375 | ECUMN_4530 | Adenylosuccinate lyase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Fused IMP cyclohydrolase; Function experimentally demonstrated in the studied species; enzyme. | 0.996 |
purB | purK | ECUMN_1375 | ECUMN_0562 | Adenylosuccinate lyase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.933 |
purB | purL | ECUMN_1375 | ECUMN_2877 | Adenylosuccinate lyase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.985 |
purB | purM | ECUMN_1375 | ECUMN_2813 | Adenylosuccinate lyase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole synthetase; Function experimentally demonstrated in the studied species; enzyme. | 0.938 |
purB | purN | ECUMN_1375 | ECUMN_2814 | Adenylosuccinate lyase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.937 |
purB | purT | ECUMN_1375 | ECUMN_2146 | Adenylosuccinate lyase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.472 |
purC | purB | ECUMN_2789 | ECUMN_1375 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the SAICAR synthetase family. | Adenylosuccinate lyase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.994 |
purC | purD | ECUMN_2789 | ECUMN_4529 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide synthetase phosphoribosylamine-glycine ligase; Function experimentally demonstrated in the studied species; enzyme. | 0.954 |
purC | purE | ECUMN_2789 | ECUMN_0563 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the SAICAR synthetase family. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.997 |
purC | purF | ECUMN_2789 | ECUMN_2652 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.927 |
purC | purH | ECUMN_2789 | ECUMN_4530 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the SAICAR synthetase family. | Fused IMP cyclohydrolase; Function experimentally demonstrated in the studied species; enzyme. | 0.957 |
purC | purK | ECUMN_2789 | ECUMN_0562 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the SAICAR synthetase family. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.978 |
purC | purL | ECUMN_2789 | ECUMN_2877 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the SAICAR synthetase family. | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.988 |
purC | purM | ECUMN_2789 | ECUMN_2813 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole synthetase; Function experimentally demonstrated in the studied species; enzyme. | 0.963 |
purC | purN | ECUMN_2789 | ECUMN_2814 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.944 |
purC | purT | ECUMN_2789 | ECUMN_2146 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.870 |