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alr alr ddlB ddlB ddlA ddlA murF murF dadA dadA dadX dadX yfbQ yfbQ dnaB dnaB murI murI murD murD nadD nadD
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
alrAlanine racemase 1, PLP-binding, biosynthetic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (359 aa)    
Predicted Functional Partners:
ddlB
D-alanine:D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.973
ddlA
D-alanine-D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.971
murF
UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
   
 0.953
dadA
D-amino acid dehydrogenase; Oxidative deamination of D-amino acids; Belongs to the DadA oxidoreductase family.
  
 
 0.940
dadX
Fragment of conserved hypothetical protein (partial); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
  
 
0.908
yfbQ
Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.817
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
 
   
 0.718
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
   
 0.695
murD
UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
 
 
 0.587
nadD
Nicotinic acid mononucleotide adenylyltransferase, NAD(P)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
  
 0.572
Your Current Organism:
Escherichia coli IAI39
NCBI taxonomy Id: 585057
Other names: E. coli IAI39
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