STRINGSTRING
ESR1 ESR1 EP300 EP300 ESR2 ESR2 PGR PGR NRIP1 NRIP1 CREBBP CREBBP BRCA1 BRCA1 NCOA3 NCOA3 SRC SRC NCOA2 NCOA2 LOC115491349 LOC115491349
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. (621 aa)    
Predicted Functional Partners:
EP300
E1A binding protein p300.
    
 0.967
ESR2
Uncharacterized protein.
  
 
0.955
PGR
Progesterone receptor.
   
0.947
NRIP1
Nuclear receptor interacting protein 1.
    
 0.940
CREBBP
CREB binding protein.
    
 0.927
BRCA1
Uncharacterized protein.
    
 
 0.921
NCOA3
Nuclear receptor coactivator.
    
 0.897
SRC
Tyrosine-protein kinase.
    
 0.884
NCOA2
Nuclear receptor coactivator.
    
 0.875
LOC115491349
Transcription factor Sp1.
    
 0.859
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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