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hemL hemL AAZ59071.1 AAZ59071.1 hemA hemA hemC hemC AAZ57593.1 AAZ57593.1 AAZ58970.1 AAZ58970.1 AAZ58991.1 AAZ58991.1 hemE hemE AAZ58786.1 AAZ58786.1 guaA guaA AAZ59305.1 AAZ59305.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
hemLGlutamate-1-semialdehyde 2,1-aminomutase; Alternative locus ID: NATL2_05221; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (432 aa)    
Predicted Functional Partners:
AAZ59071.1
Porphobilinogen synthase; Alternative locus ID: NATL2_02731; Belongs to the ALAD family.
 
 
 0.992
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.989
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
  
 0.889
AAZ57593.1
Protein of unknown function DUF92, transmembrane; Alternative locus ID: NATL2_07071.
 
      0.662
AAZ58970.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
  
 0.644
AAZ58991.1
Malonyl CoA-acyl carrier protein transacylase; Alternative locus ID: NATL2_01891.
    
 0.593
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.548
AAZ58786.1
uroporphyrinogen-III C-methyltransferase; Alternative locus ID: NATL2_21231.
 
   
 0.529
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.525
AAZ59305.1
Exodeoxyribonuclease III; Alternative locus ID: NATL2_05231.
       0.525
Your Current Organism:
Prochlorococcus marinus NATL2A
NCBI taxonomy Id: 59920
Other names: P. marinus str. NATL2A, Prochlorococcus marinus str. NATL2A, Prochlorococcus sp. NATL2A
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