STRINGSTRING
bioB bioB bioD bioD bioA bioA birA birA bioF bioF ABM77746.1 ABM77746.1 dacA dacA uppS uppS lysA lysA ABM77741.1 ABM77741.1 thiF thiF
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (335 aa)    
Predicted Functional Partners:
bioD
Putative Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.998
bioA
Putative diaminopelargonic acid synthase; COG161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.988
birA
Putative Biotin--acetyl-CoA-carboxylase ligase; COG340 Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism].
  
 
 0.943
bioF
Putative 8-amino-7-oxononanoate synthase; COG156 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism].
  
 0.855
ABM77746.1
COG1054 Predicted sulfurtransferase [General function prediction only]; Belongs to the UPF0176 family.
       0.820
dacA
Uncharacterized conserved protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
       0.771
uppS
Undecaprenyl pyrophosphate synthetase (UPPS); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
       0.771
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
     
 0.757
ABM77741.1
Putative ribosomal-protein-alanine acetyltransferase; COG456 Acetyltransferases [General function prediction only].
       0.550
thiF
Molybdopterin biosynthesis protein; COG476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism].
     
 0.518
Your Current Organism:
Prochlorococcus marinus MIT9303
NCBI taxonomy Id: 59922
Other names: P. marinus str. MIT 9303, Prochlorococcus marinus str. MIT 9303, Prochlorococcus sp. MIT 9303, Prochlorococcus sp. MIT9303
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