node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TSIB_0440 | dcd | TSIB_0440 | TSIB_0386 | Orotidine 5'-phosphate decarboxylase. | DUTPase; Catalyzes the deamination of dCTP to dUTP. | 0.493 |
TSIB_0440 | ndk | TSIB_0440 | TSIB_0535 | Orotidine 5'-phosphate decarboxylase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.443 |
TSIB_0440 | pyrE | TSIB_0440 | TSIB_0446 | Orotidine 5'-phosphate decarboxylase. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.999 |
TSIB_0440 | pyrG | TSIB_0440 | TSIB_1359 | Orotidine 5'-phosphate decarboxylase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.581 |
TSIB_1142 | dcd | TSIB_1142 | TSIB_0386 | Ribonucleotide reductase alpha subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | DUTPase; Catalyzes the deamination of dCTP to dUTP. | 0.415 |
TSIB_1142 | ndk | TSIB_1142 | TSIB_0535 | Ribonucleotide reductase alpha subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.933 |
TSIB_1142 | pyrG | TSIB_1142 | TSIB_1359 | Ribonucleotide reductase alpha subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.409 |
TSIB_1142 | tmk | TSIB_1142 | TSIB_0148 | Ribonucleotide reductase alpha subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Probable thymidylate kinase. | 0.961 |
TSIB_2048 | dcd | TSIB_2048 | TSIB_0386 | dTDP 4-dehydrorhamnose reductase. | DUTPase; Catalyzes the deamination of dCTP to dUTP. | 0.554 |
dcd | TSIB_0440 | TSIB_0386 | TSIB_0440 | DUTPase; Catalyzes the deamination of dCTP to dUTP. | Orotidine 5'-phosphate decarboxylase. | 0.493 |
dcd | TSIB_1142 | TSIB_0386 | TSIB_1142 | DUTPase; Catalyzes the deamination of dCTP to dUTP. | Ribonucleotide reductase alpha subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.415 |
dcd | TSIB_2048 | TSIB_0386 | TSIB_2048 | DUTPase; Catalyzes the deamination of dCTP to dUTP. | dTDP 4-dehydrorhamnose reductase. | 0.554 |
dcd | ndk | TSIB_0386 | TSIB_0535 | DUTPase; Catalyzes the deamination of dCTP to dUTP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.938 |
dcd | ppa | TSIB_0386 | TSIB_0025 | DUTPase; Catalyzes the deamination of dCTP to dUTP. | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.409 |
dcd | pyrE | TSIB_0386 | TSIB_0446 | DUTPase; Catalyzes the deamination of dCTP to dUTP. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.513 |
dcd | pyrG | TSIB_0386 | TSIB_1359 | DUTPase; Catalyzes the deamination of dCTP to dUTP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.933 |
dcd | thyX | TSIB_0386 | TSIB_1584 | DUTPase; Catalyzes the deamination of dCTP to dUTP. | Thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.570 |
dcd | tmk | TSIB_0386 | TSIB_0148 | DUTPase; Catalyzes the deamination of dCTP to dUTP. | Probable thymidylate kinase. | 0.637 |
dcd | tpiA | TSIB_0386 | TSIB_1685 | DUTPase; Catalyzes the deamination of dCTP to dUTP. | Triosephosphate isomerase (TIM); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.418 |
ndk | TSIB_0440 | TSIB_0535 | TSIB_0440 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Orotidine 5'-phosphate decarboxylase. | 0.443 |