STRINGSTRING
nhr-14 nhr-14 pqn-21 pqn-21 clec-150 clec-150 nlp-11 nlp-11 ptp-4 ptp-4 clec-5 clec-5 gei-8 gei-8 bed-1 bed-1 lin-17 lin-17 lin-44 lin-44 nhr-254 nhr-254
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhr-14Nuclear hormone receptor family member nhr-14; Orphan nuclear receptor. (435 aa)    
Predicted Functional Partners:
pqn-21
C2H2-type domain-containing protein.
      
 0.669
clec-150
C-type lectin domain-containing protein.
   
  
 0.627
nlp-11
Neuropeptide-like peptide 11.
   
  
 0.554
ptp-4
Tyrosine-protein phosphatase 4.
   
  
 0.546
clec-5
C-type LECtin.
   
  
 0.541
gei-8
Nuclear receptor corepressor 1; Mediates transcriptional repression by certain nuclear receptors. Plays a role in development and neuronal function. May play a role in muscle-specific oxidative mitochondrial metabolism.
    
 0.534
bed-1
BED-type domain-containing protein.
      
 0.531
lin-17
Transmembrane receptor LIN-17; Belongs to the G-protein coupled receptor Fz/Smo family.
  
    0.512
lin-44
Abnormal cell lineage protein 44; Ligand for members of the frizzled family of seven transmembrane receptors (By similarity). Affects male tail development, vulval precursor cell specification and egg laying. Involved in morphogenesis by influencing polarity of asymmetric cell divisions of the B, U, and F cells in the male, and the T cell in males and hermaphrodites. Controls spindle orientation in B-gamma cell division during male copulatory spicule development. Involved in specification of the P7.p lineage during vulval development. Has a role in providing polarity and default lin-17 [...]
  
  
 0.509
nhr-254
Nuclear Hormone Receptor family.
  
 
   0.472
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.