node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TK0556 | TK2132 | TK0556 | TK2132 | Translation initiation factor eIF-2B, beta subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Fuculose-1-phosphate aldolase. | 0.823 |
TK0556 | speE | TK0556 | TK0147 | Translation initiation factor eIF-2B, beta subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Spermidine synthase; Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high- temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to agmatine to yield N1- aminopropylagmatine. It can also use cadaverine (1,5-diaminopentane) and putrescine (1,4-diaminobutane) as substrate with a lower activity than that of agmatine. The [...] | 0.663 |
TK0556 | speH | TK0556 | TK1592 | Translation initiation factor eIF-2B, beta subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | 0.591 |
TK1595 | secD | TK1595 | TK1594 | Trk-type pottasium transport system, NAD-binding component. | Protein-export membrane protein SecD; Involved in protein export. | 0.833 |
TK1595 | secF | TK1595 | TK1593 | Trk-type pottasium transport system, NAD-binding component. | Protein-export membrane protein SecF; Involved in protein export. | 0.801 |
TK1595 | speH | TK1595 | TK1592 | Trk-type pottasium transport system, NAD-binding component. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | 0.595 |
TK2132 | TK0556 | TK2132 | TK0556 | Fuculose-1-phosphate aldolase. | Translation initiation factor eIF-2B, beta subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.823 |
TK2132 | speE | TK2132 | TK0147 | Fuculose-1-phosphate aldolase. | Spermidine synthase; Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high- temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to agmatine to yield N1- aminopropylagmatine. It can also use cadaverine (1,5-diaminopentane) and putrescine (1,4-diaminobutane) as substrate with a lower activity than that of agmatine. The [...] | 0.508 |
TK2132 | speH | TK2132 | TK1592 | Fuculose-1-phosphate aldolase. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | 0.558 |
bpsA | mat | TK1691 | TK0545 | Hypothetical protein, conserved, DUF43 family; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine. Can also use spermine to produce N(4)-aminopropylspermine. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. | 0.827 |
bpsA | speH | TK1691 | TK1592 | Hypothetical protein, conserved, DUF43 family; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine. Can also use spermine to produce N(4)-aminopropylspermine. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | 0.514 |
mat | bpsA | TK0545 | TK1691 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. | Hypothetical protein, conserved, DUF43 family; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine. Can also use spermine to produce N(4)-aminopropylspermine. | 0.827 |
mat | speH | TK0545 | TK1592 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | 0.924 |
pdaD | speE | TK0149 | TK0147 | Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family. | Spermidine synthase; Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high- temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to agmatine to yield N1- aminopropylagmatine. It can also use cadaverine (1,5-diaminopentane) and putrescine (1,4-diaminobutane) as substrate with a lower activity than that of agmatine. The [...] | 0.753 |
pdaD | speH | TK0149 | TK1592 | Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | 0.635 |
secD | TK1595 | TK1594 | TK1595 | Protein-export membrane protein SecD; Involved in protein export. | Trk-type pottasium transport system, NAD-binding component. | 0.833 |
secD | secF | TK1594 | TK1593 | Protein-export membrane protein SecD; Involved in protein export. | Protein-export membrane protein SecF; Involved in protein export. | 0.999 |
secD | speH | TK1594 | TK1592 | Protein-export membrane protein SecD; Involved in protein export. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | 0.642 |
secF | TK1595 | TK1593 | TK1595 | Protein-export membrane protein SecF; Involved in protein export. | Trk-type pottasium transport system, NAD-binding component. | 0.801 |
secF | secD | TK1593 | TK1594 | Protein-export membrane protein SecF; Involved in protein export. | Protein-export membrane protein SecD; Involved in protein export. | 0.999 |