node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADR33774.1 | ADR33840.1 | Sulku_1111 | Sulku_1177 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative transcriptional acitvator, Baf family; COGs: COG1521 Putative transcriptional regulator protein; InterPro IPR004619; KEGG: tdn:Suden_0888 pantothenate kinase; PFAM: Bvg accessory factor; SPTR: Type III pantothenate kinase; TIGRFAM: transcriptional activator, Baf family; PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: pantothenate kinase, type III. | 0.930 |
ADR33774.1 | panB | Sulku_1111 | Sulku_1985 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.444 |
ADR33774.1 | panC | Sulku_1111 | Sulku_2253 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.882 |
ADR33797.1 | guaA | Sulku_1134 | Sulku_0331 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.586 |
ADR33797.1 | panC | Sulku_1134 | Sulku_2253 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.605 |
ADR33840.1 | ADR33774.1 | Sulku_1177 | Sulku_1111 | Putative transcriptional acitvator, Baf family; COGs: COG1521 Putative transcriptional regulator protein; InterPro IPR004619; KEGG: tdn:Suden_0888 pantothenate kinase; PFAM: Bvg accessory factor; SPTR: Type III pantothenate kinase; TIGRFAM: transcriptional activator, Baf family; PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: pantothenate kinase, type III. | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.930 |
ADR33840.1 | panC | Sulku_1177 | Sulku_2253 | Putative transcriptional acitvator, Baf family; COGs: COG1521 Putative transcriptional regulator protein; InterPro IPR004619; KEGG: tdn:Suden_0888 pantothenate kinase; PFAM: Bvg accessory factor; SPTR: Type III pantothenate kinase; TIGRFAM: transcriptional activator, Baf family; PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: pantothenate kinase, type III. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.966 |
ADR33840.1 | panD | Sulku_1177 | Sulku_2287 | Putative transcriptional acitvator, Baf family; COGs: COG1521 Putative transcriptional regulator protein; InterPro IPR004619; KEGG: tdn:Suden_0888 pantothenate kinase; PFAM: Bvg accessory factor; SPTR: Type III pantothenate kinase; TIGRFAM: transcriptional activator, Baf family; PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: pantothenate kinase, type III. | L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.689 |
ADR34912.1 | ADR34916.1 | Sulku_2252 | Sulku_2256 | Hypothetical protein; KEGG: ava:Ava_3201 putative esterase; SPTR: Putative esterase. | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: sun:SUN_1325 fumarylacetoacetate hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Isomerase; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | 0.557 |
ADR34912.1 | bpt | Sulku_2252 | Sulku_2255 | Hypothetical protein; KEGG: ava:Ava_3201 putative esterase; SPTR: Putative esterase. | Arginine-tRNA-protein transferase domain protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily. | 0.557 |
ADR34912.1 | panC | Sulku_2252 | Sulku_2253 | Hypothetical protein; KEGG: ava:Ava_3201 putative esterase; SPTR: Putative esterase. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.773 |
ADR34912.1 | prfB | Sulku_2252 | Sulku_2254 | Hypothetical protein; KEGG: ava:Ava_3201 putative esterase; SPTR: Putative esterase. | Bacterial peptide chain release factor 2 (bRF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.557 |
ADR34916.1 | ADR34912.1 | Sulku_2256 | Sulku_2252 | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: sun:SUN_1325 fumarylacetoacetate hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Isomerase; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | Hypothetical protein; KEGG: ava:Ava_3201 putative esterase; SPTR: Putative esterase. | 0.557 |
ADR34916.1 | bpt | Sulku_2256 | Sulku_2255 | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: sun:SUN_1325 fumarylacetoacetate hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Isomerase; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | Arginine-tRNA-protein transferase domain protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily. | 0.773 |
ADR34916.1 | panC | Sulku_2256 | Sulku_2253 | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: sun:SUN_1325 fumarylacetoacetate hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Isomerase; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.575 |
ADR34916.1 | prfB | Sulku_2256 | Sulku_2254 | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: sun:SUN_1325 fumarylacetoacetate hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Isomerase; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | Bacterial peptide chain release factor 2 (bRF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.781 |
bpt | ADR34912.1 | Sulku_2255 | Sulku_2252 | Arginine-tRNA-protein transferase domain protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily. | Hypothetical protein; KEGG: ava:Ava_3201 putative esterase; SPTR: Putative esterase. | 0.557 |
bpt | ADR34916.1 | Sulku_2255 | Sulku_2256 | Arginine-tRNA-protein transferase domain protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily. | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: sun:SUN_1325 fumarylacetoacetate hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Isomerase; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | 0.773 |
bpt | panC | Sulku_2255 | Sulku_2253 | Arginine-tRNA-protein transferase domain protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.557 |
bpt | prfB | Sulku_2255 | Sulku_2254 | Arginine-tRNA-protein transferase domain protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily. | Bacterial peptide chain release factor 2 (bRF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.773 |