STRINGSTRING
CG11699 CG11699 Aldh-III Aldh-III Kmn1 Kmn1 CG10383 CG10383 Tusp Tusp CG4266 CG4266 CG7506 CG7506 CG12499 CG12499 l(2)k09022 l(2)k09022 Aldh Aldh dnc dnc
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG11699CG11699-RA protein. (146 aa)    
Predicted Functional Partners:
Aldh-III
Aldehyde dehydrogenase type III (Aldh-III) encodes a protein that confers a xenobiotic stress resistance by oxidising aromatic aldehydes (benzaldehyde). It also neutralises the lipid aldehydes formed after the attack of reactive oxygen and radicals, such as malondialdehyde during lipid peroxidation. The catalytic redox reaction uses NAD(P)+ as a cofactor.
    
 
 0.698
Kmn1
Kinetochore Mis12-Ndc80 network component 1 (Kmn1) encodes a protein involved in the movement of chromosomes during mitosis.
   
  
 0.662
CG10383
LD21810p; CG10383 encodes a hydrolase involved in the regulation of glycosylphosphatidylinositol metabolism, determination of lifespan and sleep.
      
 0.625
Tusp
Tusp, isoform F; Tusp (Tusp) encodes a protein involved in SNARE complex assembly; Belongs to the TUB family.
      
 0.609
CG4266
Uncharacterized protein, isoform B; mRNA binding; nucleic acid binding.
      
 0.601
CG7506
Transmembrane protein 70 homolog, mitochondrial; It is involved in the biological process described with: mitochondrial proton-transporting ATP synthase complex assembly.
   
  
 0.541
CG12499
Uncharacterized protein; It is involved in the biological process described with: maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
      
 0.523
l(2)k09022
HEAT repeat-containing protein 1 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity); Belongs to the HEATR1/UTP10 family.
      
 0.509
Aldh
Aldehyde dehydrogenase (Aldh) encodes an NAD[+] dependent mitochondrial aldehyde dehydrogenase. Its functions include detoxifying endogenous aldehydes generated by lipid peroxidation, and detoxifying acetaldehyde derived from dietary ethanol.
   
  
 0.500
dnc
Dunce (dnc) encodes a cAMP-specific phosphodiesterase, responsible for cAMP degradation. dnc product plays a pivotal role in neurological and behavioral plasticity including synaptic development and function, learning and courtship. The product of dnc is also known to affect regulation of several developmental processes such as oogenesis; Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
      
 0.491
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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