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Gapdh2 Gapdh2 Tpi Tpi Gapdh1 Gapdh1 Pgk Pgk Eno Eno Ald1 Ald1 Pgi Pgi Ald2 Ald2 PyK PyK Taldo Taldo CG8036 CG8036
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Gapdh2Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)    
Predicted Functional Partners:
Tpi
Triose phosphate isomerase (Tpi) encodes a soluble metabolic protein dimer that functions in glycolysis catalyzing the isomerization between dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, which is essential for efficient ATP production.
 
 0.999
Gapdh1
Glyceraldehyde 3 phosphate dehydrogenase 1 (Gapdh1) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glycolysis, myoblast fusion and the development of somatic muscle.
  
0.999
Pgk
Phosphoglycerate kinase (Pgk) encodes an enzyme involved in myoblast fusion; Belongs to the phosphoglycerate kinase family.
 
 0.997
Eno
Enolase (Eno) encodes a phosphopyruvate hydratase involved in glucose homeostasis; Belongs to the enolase family.
  
 
 0.995
Ald1
Fructose-bisphosphate aldolase; May take part in developmental stage-specific or tissue -specific sugar-phosphate metabolisms. Protein acts on two substrates fructose 1,6-bisphosphate and fructose 1-phosphate (like other class I aldolases).
  
 0.990
Pgi
Phosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis.
  
 
 0.989
Ald2
Fructose-bisphosphate aldolase activity. It is involved in the biological process described with: fructose 1,6-bisphosphate metabolic process; glycolytic process.
  
 0.968
PyK
Pyruvate kinase (PyK) encodes an enzyme involved in muscle development, glycolysis and glucose homeostasis; Belongs to the pyruvate kinase family.
  
 
 0.962
Taldo
Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.948
CG8036
LP07963p; Transketolase activity; thiamine pyrophosphate binding. It is involved in the biological process described with: regulation of chromatin silencing.
  
 
 0.941
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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