Peanut (pnut) encodes a protein that belongs to the septin family of polymerizing GTPases. Together with the products of Sep1 and Sep2, it forms the septin complex. It participates in cytokinesis and other processes that involve organization of the cell cortex.

Septin 5 (Sep5) encodes a member of the septin family of GTP-binding proteins. Septins form hetero-oligomeric filaments and rings that have roles in cytokinesis, cell polarity and membrane rigidity. Sep5 is not essential for development, but mutants display a synthetic lethal pupal phenotype when combined with mutations in its paralog Sep2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

Anillin; Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression and proper formation of the midbody. Required during cellularization of syncytial embryos for the proper formation and function of the furrow canals, the stable inward folds of the plasma membrane which separate the peripheral nuclei. Also required for the formation of the pole cells, the progenitors of the adult germline which are formed by cytokinesis of the cytoplasmic buds at the posterior pole of the syncytial embryo. Essential for embry [...]

Dorsal interacting protein 2; Nucleic acid binding; protein binding.

Septin interacting protein 2, isoform B; Protein binding. It is involved in the biological process described with: mitotic cytokinesis; cellular protein localization.

Septin 4, isoform A; Molecular adaptor activity; GTP binding; GTPase activity. It is involved in the biological process described with: cellular protein localization; cytoskeleton-dependent cytokinesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

SUMO-activating enzyme subunit; Ubiquitin-like activating enzyme 2 (Uba2) encodes one of two subunits (along with the product of Aos1) of the heterodimeric SUMO activating enzyme. It contains the catalytic cysteine residue that first becomes adenylated using ATP and that then forms a thioester linkage to the C-terminal end of SUMO; Belongs to the ubiquitin-activating E1 family.

Fascetto (feo) encodes a protein that binds the central spindle microtubules and is required for proper midbody formation and cytokinesis. It also has roles in centrosome duplication and neurogenesis.

Golgi phosphoprotein 3 homolog sauron; Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (By similarity). May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion (By similarity). Also involved in the control of the local [...]