STRINGSTRING
tzn tzn CG9331 CG9331 CG4229 CG4229 CG43759 CG43759 plh plh CG5334 CG5334 CG5347 CG5347 CG4390 CG4390 shop shop Glo1 Glo1 Tpst Tpst
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
tznTenzing norgay, isoform C; Hydroxyacylglutathione hydrolase activity. It is involved in the biological process described with: methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione; response to hypoxia. (348 aa)    
Predicted Functional Partners:
CG9331
GH13879p; Hydroxypyruvate reductase activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; NAD binding; glyoxylate reductase (NADP) activity; glycerate dehydrogenase activity. It is involved in the biological process described with: oxidation-reduction process; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 0.864
CG4229
LD44179p.
      
 0.838
CG43759
Uncharacterized protein, isoform B.
      
 0.796
plh
Pasang lhamu; It is involved in the biological process described with: response to hypoxia; Belongs to the peroxisomal membrane protein PXMP2/4 family.
      
 0.791
CG5334
Ubiquitin-protein transferase activity; zinc ion binding; metal ion binding; ubiquitin protein ligase activity. It is involved in the biological process described with: protein polyubiquitination.
 
 
  
 0.760
CG5347
LP05025p; Metal ion binding; ubiquitin protein ligase activity; zinc ion binding; ubiquitin-protein transferase activity. It is involved in the biological process described with: protein polyubiquitination.
 
 
  
 0.748
CG4390
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
  
  
 0.691
shop
Probable sulfite oxidase, mitochondrial; Molybdenum ion binding; sulfite oxidase activity; heme binding; molybdopterin cofactor binding. It is involved in the biological process described with: sulfur compound metabolic process; nitrate assimilation; oxidation-reduction process.
   
  
 0.684
Glo1
Glyoxalase 1; Lactoylglutathione lyase activity; metal ion binding. It is involved in the biological process described with: regulation of insulin receptor signaling pathway.
  
  
 0.673
Tpst
Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides (By similarity). Has a role in protein secretion; Belongs to the protein sulfotransferase family.
   
  
 0.670
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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