node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG3626 | CG3999 | FBpp0070620 | FBpp0081703 | FI22513p1; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.921 |
CG3626 | CG44243 | FBpp0070620 | FBpp0308231 | FI22513p1; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | LD05679p; Lipoyltransferase activity. It is involved in the biological process described with: protein lipoylation. | 0.437 |
CG3626 | CG7430 | FBpp0070620 | FBpp0074906 | FI22513p1; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | Flavin adenine dinucleotide binding; dihydrolipoyl dehydrogenase activity; electron transfer activity. It is involved in the biological process described with: tricarboxylic acid cycle; lipoamide metabolic process; oxidation-reduction process; glycine catabolic process; cell redox homeostasis. | 0.587 |
CG3626 | Gart | FBpp0070620 | FBpp0308722 | FI22513p1; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | Trifunctional purine biosynthetic protein adenosine-3; GART trifunctional enzyme (Gart) encodes a multifunctional enzyme that exhibits phosphoribosylamine-glycine ligase, phosphoribosylformylglycinamidine cyclo-ligase and phosphoribosylglycinamide formyltransferase activities; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | 0.785 |
CG3626 | Shmt | FBpp0070620 | FBpp0070792 | FI22513p1; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | Serine hydroxymethyl transferase (Shmt) encodes a conserved pyridoxal phosphate-containing enzyme that converts serine into glycine and N5,N10-methylentetrahydrofolate. This reaction represents a major source for activated C1 units and tetrahydrofolate-mediated C1 metabolism; Belongs to the SHMT family. | 0.737 |
CG3626 | Spat | FBpp0070620 | FBpp0070875 | FI22513p1; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | Serine pyruvate aminotransferase (Spat) encodes an alanine-glyoxylate transaminase involved in glyoxylate catabolism. | 0.501 |
CG3626 | ppl | FBpp0070620 | FBpp0078066 | FI22513p1; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | Glycine cleavage system H protein, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity); Belongs to the GcvH family. | 0.849 |
CG3999 | CG3626 | FBpp0081703 | FBpp0070620 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | FI22513p1; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | 0.921 |
CG3999 | CG6415 | FBpp0081703 | FBpp0079697 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.999 |
CG3999 | CG7430 | FBpp0081703 | FBpp0074906 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Flavin adenine dinucleotide binding; dihydrolipoyl dehydrogenase activity; electron transfer activity. It is involved in the biological process described with: tricarboxylic acid cycle; lipoamide metabolic process; oxidation-reduction process; glycine catabolic process; cell redox homeostasis. | 0.980 |
CG3999 | CG9804 | FBpp0081703 | FBpp0078583 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity). | 0.713 |
CG3999 | Gart | FBpp0081703 | FBpp0308722 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Trifunctional purine biosynthetic protein adenosine-3; GART trifunctional enzyme (Gart) encodes a multifunctional enzyme that exhibits phosphoribosylamine-glycine ligase, phosphoribosylformylglycinamidine cyclo-ligase and phosphoribosylglycinamide formyltransferase activities; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | 0.978 |
CG3999 | Las | FBpp0081703 | FBpp0288705 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. | 0.592 |
CG3999 | Shmt | FBpp0081703 | FBpp0070792 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Serine hydroxymethyl transferase (Shmt) encodes a conserved pyridoxal phosphate-containing enzyme that converts serine into glycine and N5,N10-methylentetrahydrofolate. This reaction represents a major source for activated C1 units and tetrahydrofolate-mediated C1 metabolism; Belongs to the SHMT family. | 0.998 |
CG3999 | Spat | FBpp0081703 | FBpp0070875 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Serine pyruvate aminotransferase (Spat) encodes an alanine-glyoxylate transaminase involved in glyoxylate catabolism. | 0.964 |
CG3999 | ppl | FBpp0081703 | FBpp0078066 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Glycine cleavage system H protein, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity); Belongs to the GcvH family. | 0.993 |
CG44243 | CG3626 | FBpp0308231 | FBpp0070620 | LD05679p; Lipoyltransferase activity. It is involved in the biological process described with: protein lipoylation. | FI22513p1; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | 0.437 |
CG44243 | CG6415 | FBpp0308231 | FBpp0079697 | LD05679p; Lipoyltransferase activity. It is involved in the biological process described with: protein lipoylation. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.437 |
CG44243 | CG7430 | FBpp0308231 | FBpp0074906 | LD05679p; Lipoyltransferase activity. It is involved in the biological process described with: protein lipoylation. | Flavin adenine dinucleotide binding; dihydrolipoyl dehydrogenase activity; electron transfer activity. It is involved in the biological process described with: tricarboxylic acid cycle; lipoamide metabolic process; oxidation-reduction process; glycine catabolic process; cell redox homeostasis. | 0.732 |
CG44243 | CG9804 | FBpp0308231 | FBpp0078583 | LD05679p; Lipoyltransferase activity. It is involved in the biological process described with: protein lipoylation. | Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity). | 0.966 |