STRINGSTRING
stc stc ms(2)35Ci ms(2)35Ci Fkbp12 Fkbp12 RpS12 RpS12 RpS15 RpS15 RpS2 RpS2 RpS13 RpS13 RpL23A RpL23A Catsup Catsup vlc vlc CG4942 CG4942
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
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[Homology]
Score
stcProtein shuttle craft; Plays an essential role during the late stages of embryonic neurogenesis. May either fine-tune the guidance or the spatial maintenance of the migrating SNB and in nerve roots, which are composed of axons originating from distinct groups of motor neurons and may be required to either guide or maintain the position of these nerves along a direct and straight path to their ultimate targets in particular muscle fields. May play a role in egg chamber development and/or may confer essential maternal contributions to the early embryo. (1106 aa)    
Predicted Functional Partners:
ms(2)35Ci
Male sterile (2) 35Ci, isoform A; It is involved in the biological process described with: spermatid differentiation.
      
 0.874
Fkbp12
12 kDa FK506-binding protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Binds to ligand-free TGF beta type I receptor, from which it is released upon a ligand-induced, type II receptor mediated phosphorylation of the type I receptor. Binding is inhibitory to the signaling pathways of the TGF beta family ligands.
   
 
 0.794
RpS12
Ribosomal protein S12 (RpS12) is an essential gene encoding a protein component of the cytoplasmic small ribosomal subunit.
    
 
 0.738
RpS15
Ribosomal protein S15 (RpS15) encodes a protein that plays a role in assembly, structure and function of the ribosome and functions in protein synthesis. It is phosphorylated by the kinase encoded by Lrrk, causing protein synthesis upregulation; Belongs to the universal ribosomal protein uS19 family.
    
   0.672
RpS2
Ribosomal protein S2 (RpS2) encodes a highly conserved component of the 40S ribolomal comlex. RpS2 product controls the assembly and nuclear export of the pre-ribosome and appears to have a specific function during oogenesis.
    
   0.672
RpS13
Ribosomal protein S13 (RpS13) encodes a structural constituent of ribosomes; Belongs to the universal ribosomal protein uS15 family.
    
   0.672
RpL23A
Ribosomal protein L23A (RpL23A) encodes an essential ribosomal RNA binding protein of the large ribosomal subunit involved in protein synthesis; Belongs to the universal ribosomal protein uL23 family.
    
   0.672
Catsup
Protein catecholamines up; Negatively regulates tyrosine hydroxylase activity; Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.
   
  
 0.670
vlc
Vulcan, isoform A; Vulcan (vlc) is induced above a basal level by 20-hydroxyecdysone in late third instar larvae. Its mutants die primarily as pharate adults with defects in ecdysone-induced leg morphogenesis.
   
  
 0.663
CG4942
LD38503p; Membrane insertase activity. It is involved in the biological process described with: protein insertion into mitochondrial inner membrane from matrix; protein insertion into membrane; mitochondrial cytochrome c oxidase assembly.
      
 0.660
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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