STRINGSTRING
ry ry Uro Uro DhpD DhpD CG18128 CG18128 shop shop CG30016 CG30016 ZnT35C ZnT35C mal mal AOX1 AOX1 AOX4 AOX4 AOX2 AOX2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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textmining
co-expression
protein homology
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ryXanthine dehydrogenase; Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid (By similarity). (1335 aa)    
Predicted Functional Partners:
Uro
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
  
 
 0.972
DhpD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Also has 7,8-dihydropterin deaminase activity, which plays a role in synthesis of the red eye pigment aurodrosopterin.
 
 
 0.958
CG18128
FI08065p; Purine-nucleoside phosphorylase activity. It is involved in the biological process described with: nucleoside metabolic process.
   
 
 0.917
shop
Probable sulfite oxidase, mitochondrial; Molybdenum ion binding; sulfite oxidase activity; heme binding; molybdopterin cofactor binding. It is involved in the biological process described with: sulfur compound metabolic process; nitrate assimilation; oxidation-reduction process.
      
 0.810
CG30016
Hydroxyisourate hydrolase activity. It is involved in the biological process described with: purine nucleobase metabolic process; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
  
 0.789
ZnT35C
Zinc transporter 35C (ZnT35C) encodes a protein involved in cellular and organismal zinc efflux that plays a major role in the detoxification of zinc excess. ZnT35C is a target of the metal-responsive transcription factor encoded by MTF-1.
    
 
 0.777
mal
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
  
  
 0.762
AOX1
Aldehyde oxidase 1 (AOX1) encodes a pyridoxal oxidase involved in pyridoxal metabolism.
  
 
0.707
AOX4
Aldehyde oxidase 4 (AOX4) encodes an oxidoreductase that catalyzes the oxidation of pyridoxal to pyridoxate with the release of hydrogen peroxide.
  
  
 
0.695
AOX2
Aldehyde oxidase 2 (AOX2) encodes a pyridoxal oxidase involved in pyridoxal metabolism.
  
  
 
0.695
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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