STRINGSTRING
140up 140up CG5569 CG5569 CG11722 CG11722 ND-19 ND-19 CIA30 CIA30 ECSIT ECSIT ND-B16.6 ND-B16.6 ND-23 ND-23 mt:ND1 mt:ND1 ND-ASHI ND-ASHI ND-PDSW ND-PDSW
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
140upRPII140-upstream gene protein; Essential for viability. (261 aa)    
Predicted Functional Partners:
CG5569
SD18780p; It is involved in the biological process described with: mitochondrial respiratory chain complex I assembly.
   
 0.996
CG11722
Protein NDUFAF4 homolog; It is involved in the biological process described with: mitochondrial respiratory chain complex I assembly; Belongs to the NDUFAF4 family.
   
 0.996
ND-19
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
 0.984
CIA30
Complex I intermediate-associated protein 30, mitochondrial; Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
   
 
 0.980
ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Involved in the innate immune response. Promotes the production of antibacterial peptides; Belongs to the ECSIT family.
   
 
 0.977
ND-B16.6
NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone.
   
 0.977
ND-23
NADH dehydrogenase (Ubiquinone) 23 kDa subunit; NADH dehydrogenase activity; 4 iron, 4 sulfur cluster binding. It is involved in the biological process described with: aerobic respiration; mitochondrial ATP synthesis coupled electron transport; mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly.
   
 0.973
mt:ND1
NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
    
 0.972
ND-ASHI
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
 0.971
ND-PDSW
NADH dehydrogenase (Ubiquinone) PDSW subunit, isoform A; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone.
   
 0.970
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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