Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ctr1B | MTF-1 | FBpp0081325 | FBpp0112234 | Copper transporter 1B (Ctr1B) encodes a protein that ensures copper uptake in the intestine. Ctr1B transcription is upregulated under conditions of copper depletion via the metal-responsive transcription factor encoded by MTF-1. | Metal response element-binding Transcription Factor-1 (MTF-1) encodes a zinc finger protein that primarily controls the homeostasis of physiological trace metals, such as zinc and copper, and the detoxification of non-essential, toxic heavy metals, such as cadmium, mercury, and silver. It activates a number of genes in response to heavy metal load but also induces transcription of the copper importer encoded by Ctr1B upon copper depletion. Variations in the DNA binding site can affect its response to a specific metal. | 0.932 |
| Ctr1B | MtnA | FBpp0081325 | FBpp0306744 | Copper transporter 1B (Ctr1B) encodes a protein that ensures copper uptake in the intestine. Ctr1B transcription is upregulated under conditions of copper depletion via the metal-responsive transcription factor encoded by MTF-1. | Metallothionein-1; Metallothionein A (MtnA) encodes a member of the Metallothionein family whose transcript level is higher than that of the other four Drosophila metallothioneins. Transcription is strongly induced by copper and cadmium ions and this induction depends on the transcription factor encoded by MTF-1; Belongs to the metallothionein superfamily. Type 5 family. | 0.627 |
| Ctr1B | MtnB | FBpp0081325 | FBpp0311981 | Copper transporter 1B (Ctr1B) encodes a protein that ensures copper uptake in the intestine. Ctr1B transcription is upregulated under conditions of copper depletion via the metal-responsive transcription factor encoded by MTF-1. | Metallothionein-2; Metallothionein B (MtnB) encodes one of the five metallothioneins. They are metal-binding polypeptides that coordinate both physiological and xenobiotic metal ions, either for homeostasis or detoxification purposes. The product of MtnB shows a preference towards divalent metal ion binding. | 0.848 |
| Ctr1B | MtnE | FBpp0081325 | FBpp0312059 | Copper transporter 1B (Ctr1B) encodes a protein that ensures copper uptake in the intestine. Ctr1B transcription is upregulated under conditions of copper depletion via the metal-responsive transcription factor encoded by MTF-1. | Metallothionein E (MtnE) encodes one of the five metallothioneins. They are metal-binding polypeptides that coordinate both physiological and xenobiotic metal ions, either for homeostasis or detoxification purposes. The product of MtnE shows the least specificity towards binding metal ions. | 0.603 |
| Ctr1B | Zip42C.2 | FBpp0081325 | FBpp0297714 | Copper transporter 1B (Ctr1B) encodes a protein that ensures copper uptake in the intestine. Ctr1B transcription is upregulated under conditions of copper depletion via the metal-responsive transcription factor encoded by MTF-1. | Zinc/iron regulated transporter-related protein 42C.2 (Zip42C.2) encodes a protein involved in zinc detoxification and zinc transmembrane import. | 0.512 |
| Ctr1B | Zip89B | FBpp0081325 | FBpp0082720 | Copper transporter 1B (Ctr1B) encodes a protein that ensures copper uptake in the intestine. Ctr1B transcription is upregulated under conditions of copper depletion via the metal-responsive transcription factor encoded by MTF-1. | Zinc/iron regulated transporter-related protein 89B (Zip89B) encodes a protein involved in zinc detoxification and zinc transmembrane import. | 0.586 |
| Ctr1B | ZnT33D | FBpp0081325 | FBpp0292109 | Copper transporter 1B (Ctr1B) encodes a protein that ensures copper uptake in the intestine. Ctr1B transcription is upregulated under conditions of copper depletion via the metal-responsive transcription factor encoded by MTF-1. | Zinc ion transmembrane transporter activity. | 0.473 |
| Ctr1B | ZnT35C | FBpp0081325 | FBpp0080274 | Copper transporter 1B (Ctr1B) encodes a protein that ensures copper uptake in the intestine. Ctr1B transcription is upregulated under conditions of copper depletion via the metal-responsive transcription factor encoded by MTF-1. | Zinc transporter 35C (ZnT35C) encodes a protein involved in cellular and organismal zinc efflux that plays a major role in the detoxification of zinc excess. ZnT35C is a target of the metal-responsive transcription factor encoded by MTF-1. | 0.812 |
| Ctr1B | ZnT63C | FBpp0081325 | FBpp0303136 | Copper transporter 1B (Ctr1B) encodes a protein that ensures copper uptake in the intestine. Ctr1B transcription is upregulated under conditions of copper depletion via the metal-responsive transcription factor encoded by MTF-1. | Zinc transporter 63C, isoform F; Zinc transporter 63C (ZnT63C) encodes a plasma membrane resident zinc transporter belonging to the zinc transporter family that is mainly responsible for zinc export from the cell or into organelles. It plays a key role in effluxing zinc from enterocytes into circulation during dietary zinc absorption. | 0.607 |
| Ctr1B | ZnT86D | FBpp0081325 | FBpp0081847 | Copper transporter 1B (Ctr1B) encodes a protein that ensures copper uptake in the intestine. Ctr1B transcription is upregulated under conditions of copper depletion via the metal-responsive transcription factor encoded by MTF-1. | Zinc transporter 86D (ZnT86D) encodes a transporter involved in zinc detoxification. | 0.442 |
| MTF-1 | Ctr1B | FBpp0112234 | FBpp0081325 | Metal response element-binding Transcription Factor-1 (MTF-1) encodes a zinc finger protein that primarily controls the homeostasis of physiological trace metals, such as zinc and copper, and the detoxification of non-essential, toxic heavy metals, such as cadmium, mercury, and silver. It activates a number of genes in response to heavy metal load but also induces transcription of the copper importer encoded by Ctr1B upon copper depletion. Variations in the DNA binding site can affect its response to a specific metal. | Copper transporter 1B (Ctr1B) encodes a protein that ensures copper uptake in the intestine. Ctr1B transcription is upregulated under conditions of copper depletion via the metal-responsive transcription factor encoded by MTF-1. | 0.932 |
| MTF-1 | MtnA | FBpp0112234 | FBpp0306744 | Metal response element-binding Transcription Factor-1 (MTF-1) encodes a zinc finger protein that primarily controls the homeostasis of physiological trace metals, such as zinc and copper, and the detoxification of non-essential, toxic heavy metals, such as cadmium, mercury, and silver. It activates a number of genes in response to heavy metal load but also induces transcription of the copper importer encoded by Ctr1B upon copper depletion. Variations in the DNA binding site can affect its response to a specific metal. | Metallothionein-1; Metallothionein A (MtnA) encodes a member of the Metallothionein family whose transcript level is higher than that of the other four Drosophila metallothioneins. Transcription is strongly induced by copper and cadmium ions and this induction depends on the transcription factor encoded by MTF-1; Belongs to the metallothionein superfamily. Type 5 family. | 0.834 |
| MTF-1 | MtnB | FBpp0112234 | FBpp0311981 | Metal response element-binding Transcription Factor-1 (MTF-1) encodes a zinc finger protein that primarily controls the homeostasis of physiological trace metals, such as zinc and copper, and the detoxification of non-essential, toxic heavy metals, such as cadmium, mercury, and silver. It activates a number of genes in response to heavy metal load but also induces transcription of the copper importer encoded by Ctr1B upon copper depletion. Variations in the DNA binding site can affect its response to a specific metal. | Metallothionein-2; Metallothionein B (MtnB) encodes one of the five metallothioneins. They are metal-binding polypeptides that coordinate both physiological and xenobiotic metal ions, either for homeostasis or detoxification purposes. The product of MtnB shows a preference towards divalent metal ion binding. | 0.840 |
| MTF-1 | MtnE | FBpp0112234 | FBpp0312059 | Metal response element-binding Transcription Factor-1 (MTF-1) encodes a zinc finger protein that primarily controls the homeostasis of physiological trace metals, such as zinc and copper, and the detoxification of non-essential, toxic heavy metals, such as cadmium, mercury, and silver. It activates a number of genes in response to heavy metal load but also induces transcription of the copper importer encoded by Ctr1B upon copper depletion. Variations in the DNA binding site can affect its response to a specific metal. | Metallothionein E (MtnE) encodes one of the five metallothioneins. They are metal-binding polypeptides that coordinate both physiological and xenobiotic metal ions, either for homeostasis or detoxification purposes. The product of MtnE shows the least specificity towards binding metal ions. | 0.837 |
| MTF-1 | Zip42C.2 | FBpp0112234 | FBpp0297714 | Metal response element-binding Transcription Factor-1 (MTF-1) encodes a zinc finger protein that primarily controls the homeostasis of physiological trace metals, such as zinc and copper, and the detoxification of non-essential, toxic heavy metals, such as cadmium, mercury, and silver. It activates a number of genes in response to heavy metal load but also induces transcription of the copper importer encoded by Ctr1B upon copper depletion. Variations in the DNA binding site can affect its response to a specific metal. | Zinc/iron regulated transporter-related protein 42C.2 (Zip42C.2) encodes a protein involved in zinc detoxification and zinc transmembrane import. | 0.511 |
| MTF-1 | Zip89B | FBpp0112234 | FBpp0082720 | Metal response element-binding Transcription Factor-1 (MTF-1) encodes a zinc finger protein that primarily controls the homeostasis of physiological trace metals, such as zinc and copper, and the detoxification of non-essential, toxic heavy metals, such as cadmium, mercury, and silver. It activates a number of genes in response to heavy metal load but also induces transcription of the copper importer encoded by Ctr1B upon copper depletion. Variations in the DNA binding site can affect its response to a specific metal. | Zinc/iron regulated transporter-related protein 89B (Zip89B) encodes a protein involved in zinc detoxification and zinc transmembrane import. | 0.415 |
| MTF-1 | ZnT35C | FBpp0112234 | FBpp0080274 | Metal response element-binding Transcription Factor-1 (MTF-1) encodes a zinc finger protein that primarily controls the homeostasis of physiological trace metals, such as zinc and copper, and the detoxification of non-essential, toxic heavy metals, such as cadmium, mercury, and silver. It activates a number of genes in response to heavy metal load but also induces transcription of the copper importer encoded by Ctr1B upon copper depletion. Variations in the DNA binding site can affect its response to a specific metal. | Zinc transporter 35C (ZnT35C) encodes a protein involved in cellular and organismal zinc efflux that plays a major role in the detoxification of zinc excess. ZnT35C is a target of the metal-responsive transcription factor encoded by MTF-1. | 0.601 |
| MTF-1 | ZnT63C | FBpp0112234 | FBpp0303136 | Metal response element-binding Transcription Factor-1 (MTF-1) encodes a zinc finger protein that primarily controls the homeostasis of physiological trace metals, such as zinc and copper, and the detoxification of non-essential, toxic heavy metals, such as cadmium, mercury, and silver. It activates a number of genes in response to heavy metal load but also induces transcription of the copper importer encoded by Ctr1B upon copper depletion. Variations in the DNA binding site can affect its response to a specific metal. | Zinc transporter 63C, isoform F; Zinc transporter 63C (ZnT63C) encodes a plasma membrane resident zinc transporter belonging to the zinc transporter family that is mainly responsible for zinc export from the cell or into organelles. It plays a key role in effluxing zinc from enterocytes into circulation during dietary zinc absorption. | 0.570 |
| MTF-1 | ZnT86D | FBpp0112234 | FBpp0081847 | Metal response element-binding Transcription Factor-1 (MTF-1) encodes a zinc finger protein that primarily controls the homeostasis of physiological trace metals, such as zinc and copper, and the detoxification of non-essential, toxic heavy metals, such as cadmium, mercury, and silver. It activates a number of genes in response to heavy metal load but also induces transcription of the copper importer encoded by Ctr1B upon copper depletion. Variations in the DNA binding site can affect its response to a specific metal. | Zinc transporter 86D (ZnT86D) encodes a transporter involved in zinc detoxification. | 0.516 |
| MtnA | Ctr1B | FBpp0306744 | FBpp0081325 | Metallothionein-1; Metallothionein A (MtnA) encodes a member of the Metallothionein family whose transcript level is higher than that of the other four Drosophila metallothioneins. Transcription is strongly induced by copper and cadmium ions and this induction depends on the transcription factor encoded by MTF-1; Belongs to the metallothionein superfamily. Type 5 family. | Copper transporter 1B (Ctr1B) encodes a protein that ensures copper uptake in the intestine. Ctr1B transcription is upregulated under conditions of copper depletion via the metal-responsive transcription factor encoded by MTF-1. | 0.627 |
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