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e e ND-ACP ND-ACP Ddc Ddc stw stw rasp rasp CG13032 CG13032 AANAT1 AANAT1 ple ple CG7924 CG7924 CarT CarT CG7906 CG7906
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query proteins and first shell of interactors
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second shell of interactors
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textmining
co-expression
protein homology
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eLP19442p; Ebony (e) encodes a protein that links beta-alanine to biogenic amines like dopamine or histamine. It controls the amount of free biogenic amine, e.g. of dopamine in cuticle formation and of histamine in visual signal transduction of the eye. It is also involved in behavioral rhythmicity. (879 aa)    
Predicted Functional Partners:
ND-ACP
Acyl carrier protein, mitochondrial; Carrier of the growing fatty acid chain in fatty acid biosynthesis. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity); Belongs to the acyl carrier protein (ACP) family.
  
 
 0.969
Ddc
Aromatic-L-amino-acid decarboxylase; Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Variation in the synthesis of bioamines may be a factor contributing to natural variation in life span. Belongs to the group II decarboxylase family.
  
  
 0.864
stw
Straw, isoform E; Oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor; ferroxidase activity; copper ion binding. It is involved in the biological process described with: oxidation-reduction process; chitin-based cuticle development; iron ion homeostasis; iron ion transport.
      
 0.859
rasp
Protein-cysteine N-palmitoyltransferase Rasp; Required in hedgehog (hh) expressing cells for production of appropriate signaling activity in embryos and in the imaginal precursors of adult tissues. Acts within the secretory pathway to catalyze N-terminal palmitoylation of Hh; this lipid modification is required for the embryonic and larval patterning activities of the Hh signal. Not required for Wg signaling.
  
  
 0.855
CG13032
FI23334p1; It is involved in the biological process described with: non-motile cilium assembly; cytoplasmic microtubule organization.
  
  
 0.855
AANAT1
Dopamine N-acetyltransferase; Catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin and octopamine. Is not essential for sclerotization.
   
  
 0.851
ple
Pale (ple) encodes a tyrosine hydroxylase, the first and rate-limiting step in the synthesis of dopamine (and eventually, melanin). Dopamine has critical roles in system development.
   
  
 0.846
CG7924
LP03067p.
   
    0.839
CarT
Carcinine transporter (CarT) encodes a transporter belonging to the SLC22A transporter family that is involved in the photoreceptor histamine-carcinine cycle. Histamine neurotransmitter is released by photoreceptors and cleared by uptake into glia, where it is converted to carcinine. The product of CarT transports carcinine back to photoreceptors, where it is hydrolysed by the product of t to restore the pool of histamine; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
      
 0.839
CG7906
Uncharacterized protein, isoform B.
   
    0.839
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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