STRINGSTRING
CG11837 CG11837 bys bys CG12325 CG12325 Tsr1 Tsr1 CG11920 CG11920 Rtc1 Rtc1 RIOK2 RIOK2 CG32533 CG32533 CG9799 CG9799 LTV1 LTV1 CG8064 CG8064
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CG11837Probable dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. (306 aa)    
Predicted Functional Partners:
bys
Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family.
   
 
 0.998
CG12325
LD10780p; It is involved in the biological process described with: ribosomal small subunit assembly; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
   
 
 0.997
Tsr1
Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus; Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.
   
 
 0.996
CG11920
FI08810p; snoRNA binding. It is involved in the biological process described with: rRNA processing.
   
   0.989
Rtc1
Probable RNA 3'-terminal phosphate cyclase-like protein; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity); Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
   
   0.987
RIOK2
RIO kinase 2; Protein kinase activity; protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: positive regulation of glial cell proliferation; maturation of SSU-rRNA; protein phosphorylation.
   
 
 0.987
CG32533
LD31543p; RNA binding; helicase activity. It is involved in the biological process described with: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.
  
 
 0.986
CG9799
LD47749p; It is involved in the biological process described with: rRNA processing.
   
   0.985
LTV1
Protein LTV1 homolog; LTV1 ribosome biogenesis factor (LTV1) encodes a protein involved in pre-rRNA processing that is required for the proper biogenesis of the 40S ribosome. LTV1 product is a direct transcriptional target of Myc, thus it is critical for cell growth and survival.
   
 
 0.985
CG8064
GH01043p; snoRNA binding. It is involved in the biological process described with: maturation of SSU-rRNA.
   
   0.984
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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