Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG18128 | Nmnat | FBpp0072003 | FBpp0084124 | FI08065p; Purine-nucleoside phosphorylase activity. It is involved in the biological process described with: nucleoside metabolic process. | Nicotinamide mononucleotide adenylyltransferase (Nmnat) encodes an essential enzyme in the NAD salvage pathway, catalyzing the last step of NAD synthesis. It is also a neuronal maintenance factor that protects neurons from excitotoxicity, environmental stress and protein misfolding induced degeneration. | 0.413 |
| CG18128 | Sirt1 | FBpp0072003 | FBpp0080015 | FI08065p; Purine-nucleoside phosphorylase activity. It is involved in the biological process described with: nucleoside metabolic process. | NAD-dependent histone deacetylase sirtuin-1; NAD-dependent histone deacetylase involved in heterochromatic silencing. Mildly suppresses the heterochromatin-mediated silencing phenomenon known as position-effect variegation (PEV). Required for epigenetic silencing of the polycomb group proteins. Has histone H4 deacetylase activity in vitro. Required maternally for establishing proper segmentation of the embryo. Involved in sex determination. May be involved in the regulation of life span. | 0.917 |
| CG18128 | Sirt7 | FBpp0072003 | FBpp0084733 | FI08065p; Purine-nucleoside phosphorylase activity. It is involved in the biological process described with: nucleoside metabolic process. | NAD-dependent protein deacetylase Sirt7; NAD-dependent protein deacetylase. | 0.909 |
| CG33156 | CG8080 | FBpp0086803 | FBpp0087714 | Uncharacterized protein, isoform E; NAD+ kinase activity. It is involved in the biological process described with: NAD metabolic process; NADP biosynthetic process. | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. | 0.985 |
| CG33156 | Nadsyn | FBpp0086803 | FBpp0073675 | Uncharacterized protein, isoform E; NAD+ kinase activity. It is involved in the biological process described with: NAD metabolic process; NADP biosynthetic process. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source (By similarity). Because of its role in energy metabolism, involved in the modulation of aged- related cardiac function, mobility, and lifespan. | 0.954 |
| CG33156 | Nmnat | FBpp0086803 | FBpp0084124 | Uncharacterized protein, isoform E; NAD+ kinase activity. It is involved in the biological process described with: NAD metabolic process; NADP biosynthetic process. | Nicotinamide mononucleotide adenylyltransferase (Nmnat) encodes an essential enzyme in the NAD salvage pathway, catalyzing the last step of NAD synthesis. It is also a neuronal maintenance factor that protects neurons from excitotoxicity, environmental stress and protein misfolding induced degeneration. | 0.956 |
| CG33156 | Sirt1 | FBpp0086803 | FBpp0080015 | Uncharacterized protein, isoform E; NAD+ kinase activity. It is involved in the biological process described with: NAD metabolic process; NADP biosynthetic process. | NAD-dependent histone deacetylase sirtuin-1; NAD-dependent histone deacetylase involved in heterochromatic silencing. Mildly suppresses the heterochromatin-mediated silencing phenomenon known as position-effect variegation (PEV). Required for epigenetic silencing of the polycomb group proteins. Has histone H4 deacetylase activity in vitro. Required maternally for establishing proper segmentation of the embryo. Involved in sex determination. May be involved in the regulation of life span. | 0.922 |
| CG33156 | Sirt7 | FBpp0086803 | FBpp0084733 | Uncharacterized protein, isoform E; NAD+ kinase activity. It is involved in the biological process described with: NAD metabolic process; NADP biosynthetic process. | NAD-dependent protein deacetylase Sirt7; NAD-dependent protein deacetylase. | 0.918 |
| CG8080 | CG33156 | FBpp0087714 | FBpp0086803 | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. | Uncharacterized protein, isoform E; NAD+ kinase activity. It is involved in the biological process described with: NAD metabolic process; NADP biosynthetic process. | 0.985 |
| CG8080 | Nadsyn | FBpp0087714 | FBpp0073675 | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source (By similarity). Because of its role in energy metabolism, involved in the modulation of aged- related cardiac function, mobility, and lifespan. | 0.948 |
| CG8080 | Nmnat | FBpp0087714 | FBpp0084124 | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. | Nicotinamide mononucleotide adenylyltransferase (Nmnat) encodes an essential enzyme in the NAD salvage pathway, catalyzing the last step of NAD synthesis. It is also a neuronal maintenance factor that protects neurons from excitotoxicity, environmental stress and protein misfolding induced degeneration. | 0.948 |
| CG8080 | Sirt1 | FBpp0087714 | FBpp0080015 | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. | NAD-dependent histone deacetylase sirtuin-1; NAD-dependent histone deacetylase involved in heterochromatic silencing. Mildly suppresses the heterochromatin-mediated silencing phenomenon known as position-effect variegation (PEV). Required for epigenetic silencing of the polycomb group proteins. Has histone H4 deacetylase activity in vitro. Required maternally for establishing proper segmentation of the embryo. Involved in sex determination. May be involved in the regulation of life span. | 0.900 |
| CG8080 | Sirt7 | FBpp0087714 | FBpp0084733 | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. | NAD-dependent protein deacetylase Sirt7; NAD-dependent protein deacetylase. | 0.900 |
| HDAC1 | HDAC11 | FBpp0073173 | FBpp0293582 | Histone deacetylase HDAC1; Catalyzes the deacetylation of lysine residues on the N- terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation may constitute a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. For instance, deacetylation of histone H3 may be a prerequisite for the subsequent recruitment of the histone methyltransferase Su(var)3-9 to histones. Involved in position-effect variegation (PEV). In the larval brain, part of a regulatory network including the transcript [...] | Histone deacetylase activity. | 0.610 |
| HDAC1 | Sirt1 | FBpp0073173 | FBpp0080015 | Histone deacetylase HDAC1; Catalyzes the deacetylation of lysine residues on the N- terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation may constitute a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. For instance, deacetylation of histone H3 may be a prerequisite for the subsequent recruitment of the histone methyltransferase Su(var)3-9 to histones. Involved in position-effect variegation (PEV). In the larval brain, part of a regulatory network including the transcript [...] | NAD-dependent histone deacetylase sirtuin-1; NAD-dependent histone deacetylase involved in heterochromatic silencing. Mildly suppresses the heterochromatin-mediated silencing phenomenon known as position-effect variegation (PEV). Required for epigenetic silencing of the polycomb group proteins. Has histone H4 deacetylase activity in vitro. Required maternally for establishing proper segmentation of the embryo. Involved in sex determination. May be involved in the regulation of life span. | 0.984 |
| HDAC1 | Sirt7 | FBpp0073173 | FBpp0084733 | Histone deacetylase HDAC1; Catalyzes the deacetylation of lysine residues on the N- terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation may constitute a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. For instance, deacetylation of histone H3 may be a prerequisite for the subsequent recruitment of the histone methyltransferase Su(var)3-9 to histones. Involved in position-effect variegation (PEV). In the larval brain, part of a regulatory network including the transcript [...] | NAD-dependent protein deacetylase Sirt7; NAD-dependent protein deacetylase. | 0.727 |
| HDAC1 | srl | FBpp0073173 | FBpp0078586 | Histone deacetylase HDAC1; Catalyzes the deacetylation of lysine residues on the N- terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation may constitute a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. For instance, deacetylation of histone H3 may be a prerequisite for the subsequent recruitment of the histone methyltransferase Su(var)3-9 to histones. Involved in position-effect variegation (PEV). In the larval brain, part of a regulatory network including the transcript [...] | Spargel, isoform B; Transcription coregulator activity; mRNA binding; nuclear receptor transcription coactivator activity; transcription factor binding; nucleic acid binding. | 0.481 |
| HDAC11 | HDAC1 | FBpp0293582 | FBpp0073173 | Histone deacetylase activity. | Histone deacetylase HDAC1; Catalyzes the deacetylation of lysine residues on the N- terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation may constitute a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. For instance, deacetylation of histone H3 may be a prerequisite for the subsequent recruitment of the histone methyltransferase Su(var)3-9 to histones. Involved in position-effect variegation (PEV). In the larval brain, part of a regulatory network including the transcript [...] | 0.610 |
| HDAC11 | Sirt1 | FBpp0293582 | FBpp0080015 | Histone deacetylase activity. | NAD-dependent histone deacetylase sirtuin-1; NAD-dependent histone deacetylase involved in heterochromatic silencing. Mildly suppresses the heterochromatin-mediated silencing phenomenon known as position-effect variegation (PEV). Required for epigenetic silencing of the polycomb group proteins. Has histone H4 deacetylase activity in vitro. Required maternally for establishing proper segmentation of the embryo. Involved in sex determination. May be involved in the regulation of life span. | 0.904 |
| HDAC11 | Sirt7 | FBpp0293582 | FBpp0084733 | Histone deacetylase activity. | NAD-dependent protein deacetylase Sirt7; NAD-dependent protein deacetylase. | 0.805 |
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