STRINGSTRING
CG7601 CG7601 hdm hdm CG5921 CG5921 mRpS18B mRpS18B Rbp Rbp lic lic beg beg scramb2 scramb2 CG12170 CG12170 Traf4 Traf4 Dhap-at Dhap-at
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG7601Dehydrogenase/reductase SDR family protein 7-like; Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (326 aa)    
Predicted Functional Partners:
hdm
Protein hold'em; Single-stranded DNA-binding protein required for meiosis. May be involved in the resolution of recombination intermediates into crossovers in the meiotic recombination pathway.
    
 
 0.916
CG5921
Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle.
    
 
 0.838
mRpS18B
Mitochondrial ribosomal protein S18B, isoform A; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.
      
 0.668
Rbp
RIM-binding protein, isoform F; RIM-binding protein (Rbp) encodes an active zone protein involved in neuromuscular synaptic transmission and presynaptic active zone organization.
      
 0.529
lic
Licorne (lic) encodes a serine/threonine kinase that phosphorylates p38 MAP kinases.
      
 0.519
beg
Probable malonyl-CoA-acyl carrier protein transacylase, mitochondrial; Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the ACP protein. This suggests the existence of the biosynthesis of fatty acids in mitochondria (By similarity).
  
 
 0.464
scramb2
Scramblase 2 (scramb2) encodes a protein that, together with the product of scramb1, has a modulatory function in the process of neurotransmission. They have a significant role in scrambling of phospholipids across the plasma membrane during apoptosis.
    
   0.420
CG12170
3-oxoacyl-[acyl-carrier-protein] synthase activity. It is involved in the biological process described with: fatty acid biosynthetic process; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 
 0.408
Traf4
TNF-receptor-associated factor 4 (Traf4) encodes an adapter protein thought to bind the TNF receptor and activate downstream signaling. However, it also has TNF independent roles, especially with respect to morphogenesis. The product of Traf4 interacts with and localizes polarity and adherens junction proteins such as the products of baz and arm respectively. It is required for normal embryonic development, cell death, and cell growth.
      
 0.407
Dhap-at
Dihydroxyacetone phosphate acyltransferase, isoform C; Glycerone-phosphate O-acyltransferase activity. It is involved in the biological process described with: fatty acid metabolic process; ether lipid biosynthetic process; phospholipid biosynthetic process; Belongs to the GPAT/DAPAT family.
      
 0.407
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.