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Cyp6g2 Cyp6g2 CG14075 CG14075 Akh Akh spok spok shd shd CG10737 CG10737 Cyp12d1-d Cyp12d1-d Cyp12d1-p Cyp12d1-p Mdr49 Mdr49 Ugt37C2 Ugt37C2 Fdx2 Fdx2
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Cyp6g2Probable cytochrome P450 6g2; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides; Belongs to the cytochrome P450 family. (519 aa)    
Predicted Functional Partners:
CG14075
GEO11536p1.
   
  
 0.567
Akh
Adipokinetic hormone (Akh) encodes a peptide hormone secreted by the corpora cardiaca. It signals to the G-protein coupled receptor encoded by AkhR to regulate circulating hemolymph carbohydrates and stored lipid and glycogen in the fat body; Belongs to the AKH/HRTH/RPCH family.
   
  
 0.545
spok
Spookier (spok) encodes a cytochrome P450 involved in ecdysteroid biosynthesis that is expressed primarily in the prothoracic gland and is localized in the endoplasmic reticulum. Genetic evidence suggests that the product of spok acts with the products of sro and Cyp6t3 to catalyze conversion of 7 dehydrocholesterol to delta4, diketol during the ecdysone biosynthetic pathway.
  
 
 0.543
shd
Ecdysone 20-monooxygenase; Shade (shd) encodes 20-hydroxylase and is responsible for converting Ecdysone into 20-hydroxyecdysone, the active form of the steroid. It is required in all tissues that produce active Ecdysone and thus contributes to larval moulting, metamorphosis, growth, neuroblast diversity and egg chamber maturation; Belongs to the cytochrome P450 family.
  
 
   0.531
CG10737
Uncharacterized protein, isoform T; It is involved in the biological process described with: intracellular signal transduction.
    
 
 0.524
Cyp12d1-d
Probable cytochrome P450 12d1 distal, mitochondrial; Cyp12d1-d (Cyp12d1-d) encodes a protein involved in the response to the insecticide dichlorodiphenyltrichloroethane (DDT).
  
 
 
0.514
Cyp12d1-p
Probable cytochrome P450 12d1 proximal, mitochondrial; Cyp12d1-p (Cyp12d1-p) encodes a protein involved in the response to the insecticide dichlorodiphenyltrichloroethane (DDT).
  
 
 
0.508
Mdr49
Multidrug resistance protein homolog 49; Multi drug resistance 49 (Mdr49) encodes drug transmembrane transporter that belongs to the ABCB transporter subfamily and contributes to insecticide resistance.
   
  
 0.480
Ugt37C2
UDP-glycosyltransferase family 37 member C2, isoform A; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity.
   
 
 0.474
Fdx2
Adrenodoxin-like protein 2, mitochondrial; Required for ecdysteroidogenesis in the prothoracic gland which is necessary for larval to pupal transition. Belongs to the adrenodoxin/putidaredoxin family.
  
 
 0.473
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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