node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atpalpha | CG10226 | FBpp0088502 | FBpp0076720 | Sodium/potassium-transporting ATPase subunit alpha; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Uncharacterized protein, isoform A; Efflux transmembrane transporter activity; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity; ATPase-coupled xenobiotic transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; xenobiotic transport. | 0.798 |
Atpalpha | CG11703 | FBpp0088502 | FBpp0083158 | Sodium/potassium-transporting ATPase subunit alpha; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Na/K-ATPase beta subunit isoform 4; Sodium:potassium-exchanging ATPase activity; ATPase activator activity. It is involved in the biological process described with: cellular sodium ion homeostasis; sodium ion export across plasma membrane; potassium ion import across plasma membrane; cellular potassium ion homeostasis. | 0.791 |
Atpalpha | Mdr65 | FBpp0088502 | FBpp0076719 | Sodium/potassium-transporting ATPase subunit alpha; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Multidrug resistance protein homolog 65; Multi drug resistance 65 (Mdr65) encodes a member of the MRP/ABCC subfamily of ATP-binding cassette (ABC) transporters. It is involved in humoral/CNS barrier drug exclusion and response to insecticide; Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. | 0.915 |
Atpalpha | Nrg | FBpp0088502 | FBpp0297081 | Sodium/potassium-transporting ATPase subunit alpha; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Neuroglian; The long isoform may play a role in neural and glial cell adhesion in the developing embryo. The short isoform may be a more general cell adhesion molecule involved in other tissues and imaginal disk morphogenesis. Vital for embryonic development. Essential for septate junctions. Septate junctions, which are the equivalent of vertebrates tight junctions, are characterized by regular arrays of transverse structures that span the intermembrane space and form a physical barrier to diffusion. Required for the blood-brain barrier formation. | 0.909 |
Atpalpha | Nrx-IV | FBpp0088502 | FBpp0075730 | Sodium/potassium-transporting ATPase subunit alpha; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Neurexin-4; Seems to play a role in the formation and function of septate junctions. Septate junctions, which are the equivalent of vertebrates tight junctions, are characterized by regular arrays of transverse structures that span the intermembrane space and form a physical barrier to diffusion. Required for the blood-brain barrier formation. Belongs to the neurexin family. | 0.943 |
Atpalpha | Ube3a | FBpp0088502 | FBpp0075916 | Sodium/potassium-transporting ATPase subunit alpha; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Ubiquitin protein ligase E3A (Ube3a) encodes the founding member of the HECT-type ubiquitin E3 ligase family of enzymes. It is involved in the final step of conjugation of ubiquitin to its target substrates. It regulates protein degradation by targeting modified proteins to the proteasome or by regulating the proteasome activity through ubiquitination of its subunits, which in turn affects many aspects of neuronal function, such as synaptic plasticity, long-term memory or dendritic development. | 0.766 |
Atpalpha | nrv1 | FBpp0088502 | FBpp0079012 | Sodium/potassium-transporting ATPase subunit alpha; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. | 0.990 |
Atpalpha | nrv2 | FBpp0088502 | FBpp0079009 | Sodium/potassium-transporting ATPase subunit alpha; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Sodium/potassium-transporting ATPase subunit beta-2; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. | 0.997 |
Atpalpha | nrv3 | FBpp0088502 | FBpp0305547 | Sodium/potassium-transporting ATPase subunit alpha; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Nervana 3 (nrv3) encodes one of three beta subunits of the sodium-potassium pump (ATPalpha). nrv3 is expressed in the nervous system, including subsets of the CNS and Johnston's organ neurons, and is required for hearing. | 0.967 |
Atpalpha | sinu | FBpp0088502 | FBpp0076842 | Sodium/potassium-transporting ATPase subunit alpha; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Sinuous (sinu) encodes a claudin that contributes to the assembly of septate junctions. It is involved in the development of heart, tracheal tree and the glial blood-brain barrier. | 0.796 |
CG10226 | Atpalpha | FBpp0076720 | FBpp0088502 | Uncharacterized protein, isoform A; Efflux transmembrane transporter activity; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity; ATPase-coupled xenobiotic transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; xenobiotic transport. | Sodium/potassium-transporting ATPase subunit alpha; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | 0.798 |
CG10226 | CG11703 | FBpp0076720 | FBpp0083158 | Uncharacterized protein, isoform A; Efflux transmembrane transporter activity; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity; ATPase-coupled xenobiotic transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; xenobiotic transport. | Na/K-ATPase beta subunit isoform 4; Sodium:potassium-exchanging ATPase activity; ATPase activator activity. It is involved in the biological process described with: cellular sodium ion homeostasis; sodium ion export across plasma membrane; potassium ion import across plasma membrane; cellular potassium ion homeostasis. | 0.546 |
CG10226 | Mdr65 | FBpp0076720 | FBpp0076719 | Uncharacterized protein, isoform A; Efflux transmembrane transporter activity; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity; ATPase-coupled xenobiotic transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; xenobiotic transport. | Multidrug resistance protein homolog 65; Multi drug resistance 65 (Mdr65) encodes a member of the MRP/ABCC subfamily of ATP-binding cassette (ABC) transporters. It is involved in humoral/CNS barrier drug exclusion and response to insecticide; Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. | 0.739 |
CG10226 | nrv1 | FBpp0076720 | FBpp0079012 | Uncharacterized protein, isoform A; Efflux transmembrane transporter activity; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity; ATPase-coupled xenobiotic transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; xenobiotic transport. | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. | 0.836 |
CG10226 | nrv2 | FBpp0076720 | FBpp0079009 | Uncharacterized protein, isoform A; Efflux transmembrane transporter activity; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity; ATPase-coupled xenobiotic transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; xenobiotic transport. | Sodium/potassium-transporting ATPase subunit beta-2; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. | 0.724 |
CG10226 | nrv3 | FBpp0076720 | FBpp0305547 | Uncharacterized protein, isoform A; Efflux transmembrane transporter activity; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity; ATPase-coupled xenobiotic transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; xenobiotic transport. | Nervana 3 (nrv3) encodes one of three beta subunits of the sodium-potassium pump (ATPalpha). nrv3 is expressed in the nervous system, including subsets of the CNS and Johnston's organ neurons, and is required for hearing. | 0.552 |
CG11703 | Atpalpha | FBpp0083158 | FBpp0088502 | Na/K-ATPase beta subunit isoform 4; Sodium:potassium-exchanging ATPase activity; ATPase activator activity. It is involved in the biological process described with: cellular sodium ion homeostasis; sodium ion export across plasma membrane; potassium ion import across plasma membrane; cellular potassium ion homeostasis. | Sodium/potassium-transporting ATPase subunit alpha; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | 0.791 |
CG11703 | CG10226 | FBpp0083158 | FBpp0076720 | Na/K-ATPase beta subunit isoform 4; Sodium:potassium-exchanging ATPase activity; ATPase activator activity. It is involved in the biological process described with: cellular sodium ion homeostasis; sodium ion export across plasma membrane; potassium ion import across plasma membrane; cellular potassium ion homeostasis. | Uncharacterized protein, isoform A; Efflux transmembrane transporter activity; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity; ATPase-coupled xenobiotic transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; xenobiotic transport. | 0.546 |
CG11703 | Mdr65 | FBpp0083158 | FBpp0076719 | Na/K-ATPase beta subunit isoform 4; Sodium:potassium-exchanging ATPase activity; ATPase activator activity. It is involved in the biological process described with: cellular sodium ion homeostasis; sodium ion export across plasma membrane; potassium ion import across plasma membrane; cellular potassium ion homeostasis. | Multidrug resistance protein homolog 65; Multi drug resistance 65 (Mdr65) encodes a member of the MRP/ABCC subfamily of ATP-binding cassette (ABC) transporters. It is involved in humoral/CNS barrier drug exclusion and response to insecticide; Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. | 0.546 |
CG11703 | nrv1 | FBpp0083158 | FBpp0079012 | Na/K-ATPase beta subunit isoform 4; Sodium:potassium-exchanging ATPase activity; ATPase activator activity. It is involved in the biological process described with: cellular sodium ion homeostasis; sodium ion export across plasma membrane; potassium ion import across plasma membrane; cellular potassium ion homeostasis. | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. | 0.594 |