STRINGSTRING
Drip Drip AQP AQP rnh1 rnh1 P5CS P5CS Eglp1 Eglp1 CG34054 CG34054 CG30026 CG30026 Gpo2 Gpo2 Gpo1 Gpo1 Gpo3 Gpo3 MED1 MED1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DripAquaporin; Drip (Drip) encodes a protein that belongs to the MIP/aquaporin family involved in the transport of water across the cell membrane. In addition to its cellular roles, it has been implicated in regulating aspects of reproduction and aging. (278 aa)    
Predicted Functional Partners:
AQP
Aquaporin; Channel activity; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.959
rnh1
Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
     
 0.837
P5CS
Delta-1-pyrroline-5-carboxylate synthase; Glutamate-5-semialdehyde dehydrogenase activity; glutamate 5-kinase activity; delta1-pyrroline-5-carboxylate synthetase activity. It is involved in the biological process described with: oxidation-reduction process; proline biosynthetic process; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.667
Eglp1
Entomoglyceroporin 1; Water channel activity; channel activity. It is involved in the biological process described with: transmembrane transport; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.644
CG34054
GEO11132p1.
   
 
 0.638
CG30026
Uncharacterized protein.
   
 
 0.635
Gpo2
Glycerol-3-phosphate dehydrogenase (quinone) activity; calcium ion binding. It is involved in the biological process described with: glycerol metabolic process; glycerol-3-phosphate metabolic process; oxidation-reduction process; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.595
Gpo1
Glycerol-3-phosphate dehydrogenase; Glycerophosphate oxidase 1 (Gpo1) encodes a mitochondrial inner membrane protein with glycerol-3-phosphate dehydrogenase activity; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.595
Gpo3
Glycerol-3-phosphate dehydrogenase (quinone) activity. It is involved in the biological process described with: oxidation-reduction process; glycerol-3-phosphate metabolic process; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.595
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required [...]
      
 0.582
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.