node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADY50715.1 | ADY50722.1 | Pedsa_0129 | Pedsa_0136 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR 005311: IPR 001460; KEGG: phe:Phep_3331 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain. | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Cell division protein FtsQ. | 0.976 |
ADY50715.1 | ADY51555.1 | Pedsa_0129 | Pedsa_0984 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR 005311: IPR 001460; KEGG: phe:Phep_3331 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.723 |
ADY50715.1 | ADY51919.1 | Pedsa_0129 | Pedsa_1352 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR 005311: IPR 001460; KEGG: phe:Phep_3331 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain. | Mur ligase middle domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713: IPR 013221; KEGG: phe:Phep_1570 cytoplasmic peptidoglycan synthetase domain protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR:UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl -meso-diaminopimelateligase; PFAM: Mur ligase family, catalytic domain; Mur ligase middle domain. | 0.496 |
ADY50715.1 | ddl | Pedsa_0129 | Pedsa_1076 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR 005311: IPR 001460; KEGG: phe:Phep_3331 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain. | D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.711 |
ADY50715.1 | ftsA | Pedsa_0129 | Pedsa_0137 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR 005311: IPR 001460; KEGG: phe:Phep_3331 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.802 |
ADY50715.1 | murC | Pedsa_0129 | Pedsa_0135 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR 005311: IPR 001460; KEGG: phe:Phep_3331 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.908 |
ADY50715.1 | murD | Pedsa_0129 | Pedsa_0132 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR 005311: IPR 001460; KEGG: phe:Phep_3331 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.965 |
ADY50715.1 | murE | Pedsa_0129 | Pedsa_0130 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR 005311: IPR 001460; KEGG: phe:Phep_3331 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.975 |
ADY50715.1 | murF | Pedsa_0129 | Pedsa_2850 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR 005311: IPR 001460; KEGG: phe:Phep_3331 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.790 |
ADY50715.1 | murG | Pedsa_0129 | Pedsa_0134 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR 005311: IPR 001460; KEGG: phe:Phep_3331 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.873 |
ADY50722.1 | ADY50715.1 | Pedsa_0136 | Pedsa_0129 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Cell division protein FtsQ. | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR 005311: IPR 001460; KEGG: phe:Phep_3331 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain. | 0.976 |
ADY50722.1 | ADY51555.1 | Pedsa_0136 | Pedsa_0984 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Cell division protein FtsQ. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.861 |
ADY50722.1 | ADY51919.1 | Pedsa_0136 | Pedsa_1352 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Cell division protein FtsQ. | Mur ligase middle domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713: IPR 013221; KEGG: phe:Phep_1570 cytoplasmic peptidoglycan synthetase domain protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR:UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl -meso-diaminopimelateligase; PFAM: Mur ligase family, catalytic domain; Mur ligase middle domain. | 0.804 |
ADY50722.1 | ddl | Pedsa_0136 | Pedsa_1076 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Cell division protein FtsQ. | D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.830 |
ADY50722.1 | ftsA | Pedsa_0136 | Pedsa_0137 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Cell division protein FtsQ. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.987 |
ADY50722.1 | murC | Pedsa_0136 | Pedsa_0135 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Cell division protein FtsQ. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.965 |
ADY50722.1 | murD | Pedsa_0136 | Pedsa_0132 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Cell division protein FtsQ. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.947 |
ADY50722.1 | murE | Pedsa_0136 | Pedsa_0130 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Cell division protein FtsQ. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.818 |
ADY50722.1 | murF | Pedsa_0136 | Pedsa_2850 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Cell division protein FtsQ. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.600 |
ADY50722.1 | murG | Pedsa_0136 | Pedsa_0134 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Cell division protein FtsQ. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.980 |