STRINGSTRING
HDAC1 HDAC1 W4Y269_STRPU W4Y269_STRPU W4YZA2_STRPU W4YZA2_STRPU W4YRU6_STRPU W4YRU6_STRPU W4YI24_STRPU W4YI24_STRPU W4Z7E6_STRPU W4Z7E6_STRPU W4XKM5_STRPU W4XKM5_STRPU W4ZCX0_STRPU W4ZCX0_STRPU W4XYV6_STRPU W4XYV6_STRPU W4YWY7_STRPU W4YWY7_STRPU W4XJD3_STRPU W4XJD3_STRPU
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). (576 aa)    
Predicted Functional Partners:
W4Y269_STRPU
ARID domain-containing protein.
   
 0.985
W4YZA2_STRPU
Tudor domain-containing protein.
   
 0.985
W4YRU6_STRPU
Uncharacterized protein.
    
 0.937
W4YI24_STRPU
HDAC_interact domain-containing protein.
   
 0.927
W4Z7E6_STRPU
Uncharacterized protein.
   
 0.910
W4XKM5_STRPU
Uncharacterized protein.
   
 0.907
W4ZCX0_STRPU
Uncharacterized protein.
   
 0.907
W4XYV6_STRPU
Uncharacterized protein.
   
 0.903
W4YWY7_STRPU
Uncharacterized protein.
     
  0.900
W4XJD3_STRPU
Uncharacterized protein.
    
 0.899
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
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