STRINGSTRING
tbx16 tbx16 noto noto msgn1 msgn1 tdgf1 tdgf1 sox32 sox32 pcdh8 pcdh8 ndr1 ndr1 chrd chrd znfl2a znfl2a foxh1 foxh1 eve1 eve1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbx16T-box transcription factor 16. (470 aa)    
Predicted Functional Partners:
noto
Notochord homeobox.
   
  
 0.894
msgn1
Mesogenin-1; Involved in specifying the paraxial, but not dorsal, mesoderm. May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation (By similarity).
   
 
 0.881
tdgf1
Teratocarcinoma-derived growth factor 1.
   
  
 0.772
sox32
SRY-box transcription factor 32.
   
 
 0.765
pcdh8
Protocadherin 8.
   
  
 0.757
ndr1
Nodal-related 1.
  
  
 0.735
chrd
Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity); Belongs to the chordin family.
   
  
 0.709
znfl2a
Zinc finger-like gene 2a.
   
 
 0.678
foxh1
Forkhead box protein H1; Transcriptional activator. Activates an activin response element (ARE). Recognizes and binds to the DNA sequence 5'- TGT[GT][GT]ATT-3'. Modulator of nodal signaling required for organizer formation. Also required for the development of dorsal axial structures and left-right symmetry.
   
  
 0.675
eve1
Even-skipped-like1.
   
 
 0.655
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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