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ttc26 ttc26 ift46 ift46 ift88 ift88 flr flr ift57 ift57 ift52 ift52 ift81 ift81 ift80 ift80 ift172 ift172 ift22 ift22 cluap1 cluap1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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ttc26Intraflagellar transport protein 56; Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components. Essential for maintaining proper microtubule organization within the ciliary axoneme (By similarity). Belongs to the IFT56 family. (557 aa)    
Predicted Functional Partners:
ift46
Intraflagellar transport protein 46 homolog; Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Plays a role in early embryonic development; Belongs to the IFT46 family.
  
 0.999
ift88
Intraflagellar transport 88 homolog.
  
 0.998
flr
Tetratricopeptide repeat protein 30A; Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (By similarity). Required for polyglutamylation of axonemal tubulin, which is a prerequisite for correct assembly of cilia and for normal cilia beat amplitude. Does not seem to be required for neuronal microtubule polyglutamylation.
   
 0.998
ift57
Intraflagellar transport protein 57 homolog; Required for the formation of cilia. Essential for differentiation and survival of sensory neurons. May also have pro- apoptotic function.
  
 0.997
ift52
Intraflagellar transport 52 homolog (Chlamydomonas).
   
 0.997
ift81
Intraflagellar transport 81 homolog.
   
 0.996
ift80
Intraflagellar transport 80 homolog (Chlamydomonas).
  
 0.993
ift172
Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia.
   
 0.992
ift22
Intraflagellar transport protein 22 homolog; Belongs to the small GTPase superfamily. Rab family.
   
 0.990
cluap1
Clusterin-associated protein 1 homolog; Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Belongs to the CLUAP1 family.
  
 0.990
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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