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akr1a1a akr1a1a aldh3b1 aldh3b1 aldh3b2 aldh3b2 cryl1 cryl1 GK3P GK3P gusb gusb mgll mgll kl kl akr1a1b akr1a1b gkup gkup miox miox
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
akr1a1aAldo-keto reductase family 1 member A1-A; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids. Acts as an aldehyde-detoxification enzyme (By similarity). Displays no reductase activity towards retinoids (By similarity). (324 aa)    
Predicted Functional Partners:
aldh3b1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.949
aldh3b2
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.949
cryl1
Crystallin, lambda 1.
   
 
 0.922
GK3P
Zgc:172295; Belongs to the FGGY kinase family.
  
 
 0.920
gusb
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
  
 
 0.917
mgll
Monoglyceride lipase.
   
 
 0.908
kl
Klotho.
     
 0.908
akr1a1b
Aldo-keto reductase family 1 member A1-B; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids. Acts as an aldehyde-detoxification enzyme (By similarity). Displays no reductase activity towards retinoids (By similarity).
  
 
0.906
gkup
Glucuronokinase with putative uridyl pyrophosphorylase.
   
 
 0.903
miox
Inositol oxygenase; Belongs to the myo-inositol oxygenase family.
 
 
 
 0.851
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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