STRINGSTRING
gsx1 gsx1 mtif3 mtif3 olig2 olig2 sp8a sp8a abhd10a abhd10a gad1b gad1b ascl1a ascl1a gtf3ab gtf3ab lhx5 lhx5 lhx9 lhx9 lhx6 lhx6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gsx1Genetic screen homeobox 1 protein. (243 aa)    
Predicted Functional Partners:
mtif3
Mitochondrial translational initiation factor 3.
      
 0.670
olig2
Oligodendrocyte lineage transcription factor 2.
   
  
 0.575
sp8a
Sp8 transcription factor a.
    
 
 0.569
abhd10a
Abhydrolase domain-containing 10a.
      
 0.563
gad1b
Glutamate decarboxylase 1b.
      
 0.554
ascl1a
Achaete-scute homolog 1a; Transcriptional regulator. May mediate transcription activation by binding to the E box-containing promoter (By similarity). Involved in neurogenesis. Required for the development of neurons in the epiphysis, acting partially redundantly with neurog1 and downstream of flh. Involved in maintaining rhombomere boundaries in the hindbrain, probably via up-regulation of delta expression. Also involved in pituitary development; required cell-autonomously in adenohypophyseal cells for endocrine differentiation and for survival of a subset of cells.
   
 
 0.550
gtf3ab
General transcription factor IIIA, b.
    
 
 0.535
lhx5
LIM/homeobox protein Lhx5; Probably involved in the patterning of the nervous system, in particular in the early specification of the diencephalon.
    
 
 0.500
lhx9
LIM/homeobox protein Lhx9; May be involved in gonadal development.
   
 
 0.499
lhx6
LIM homeobox 6.
    
 
 0.497
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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