STRINGSTRING
kat7a kat7a meaf6 meaf6 trrap trrap dmap1 dmap1 yeats4 yeats4 ing5a ing5a ing4 ing4 morf4l1 morf4l1 ruvbl1 ruvbl1 jade1 jade1 jade3 jade3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
kat7aK(lysine) acetyltransferase 7a. (128 aa)    
Predicted Functional Partners:
meaf6
Chromatin modification-related protein MEAF6; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vi [...]
    
 0.836
trrap
Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.
   
 
 0.705
dmap1
DNA methyltransferase 1-associated protein 1.
   
 
 0.698
yeats4
YEATS domain-containing 4.
    
 
 0.667
ing5a
Inhibitor of growth protein.
    
 0.662
ing4
Inhibitor of growth protein.
    
 0.662
morf4l1
Mortality factor 4-like 1.
   
 
 0.661
ruvbl1
RuvB-like 1; Has single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity). Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP- dependent nucleosome sliding (By similarity). May act as a negative regulator of embryonic heart growth. Belongs to the RuvB family.
   
 
 0.640
jade1
Protein Jade-1; Transcriptional coactivator which seems to act by promoting acetylation of nucleosomal histone H4 by kat5. Promotes apoptosis (By similarity).
   
 0.630
jade3
Protein Jade-3; May regulate histone acetylation.
    
 0.629
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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