node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
abhd11 | abhd18 | ENSDARP00000091982 | ENSDARP00000136479 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Abhydrolase domain-containing 18. | 0.854 |
abhd11 | abhd2a | ENSDARP00000091982 | ENSDARP00000035450 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | 0.760 |
abhd11 | abhd3 | ENSDARP00000091982 | ENSDARP00000004474 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Abhydrolase domain-containing 3. | 0.668 |
abhd11 | abhd4 | ENSDARP00000091982 | ENSDARP00000137303 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Abhydrolase domain-containing 4. | 0.695 |
abhd11 | abhd8a | ENSDARP00000091982 | ENSDARP00000132534 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Abhydrolase domain-containing 8a. | 0.801 |
abhd11 | bysl | ENSDARP00000091982 | ENSDARP00000001346 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Bystin-like. | 0.618 |
abhd11 | derl1 | ENSDARP00000091982 | ENSDARP00000036613 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.618 |
abhd11 | mak16 | ENSDARP00000091982 | ENSDARP00000098580 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Protein MAK16 homolog; Plays an essential role in early embryonic development. | 0.734 |
abhd11 | twistnb | ENSDARP00000091982 | ENSDARP00000104602 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | DNA-directed RNA polymerase I subunit RPA43; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. May be involved in recruitment of Pol I to rDNA promoters (By similarity). | 0.722 |
abhd11 | utp11 | ENSDARP00000091982 | ENSDARP00000058459 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. | 0.682 |
abhd18 | abhd11 | ENSDARP00000136479 | ENSDARP00000091982 | Abhydrolase domain-containing 18. | Protein ABHD11; Belongs to the AB hydrolase superfamily. | 0.854 |
abhd18 | abhd2a | ENSDARP00000136479 | ENSDARP00000035450 | Abhydrolase domain-containing 18. | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | 0.839 |
abhd18 | abhd3 | ENSDARP00000136479 | ENSDARP00000004474 | Abhydrolase domain-containing 18. | Abhydrolase domain-containing 3. | 0.720 |
abhd18 | abhd4 | ENSDARP00000136479 | ENSDARP00000137303 | Abhydrolase domain-containing 18. | Abhydrolase domain-containing 4. | 0.808 |
abhd18 | abhd8a | ENSDARP00000136479 | ENSDARP00000132534 | Abhydrolase domain-containing 18. | Abhydrolase domain-containing 8a. | 0.939 |
abhd2a | abhd11 | ENSDARP00000035450 | ENSDARP00000091982 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Protein ABHD11; Belongs to the AB hydrolase superfamily. | 0.760 |
abhd2a | abhd18 | ENSDARP00000035450 | ENSDARP00000136479 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Abhydrolase domain-containing 18. | 0.839 |
abhd2a | abhd3 | ENSDARP00000035450 | ENSDARP00000004474 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Abhydrolase domain-containing 3. | 0.409 |
abhd2a | abhd4 | ENSDARP00000035450 | ENSDARP00000137303 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Abhydrolase domain-containing 4. | 0.771 |
abhd2a | abhd8a | ENSDARP00000035450 | ENSDARP00000132534 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Abhydrolase domain-containing 8a. | 0.769 |