STRINGSTRING
znf516 znf516 SLC66A2 SLC66A2 rbfa rbfa hsbp1l1 hsbp1l1 ice2 ice2 kdm1a kdm1a MAP3K13 MAP3K13 txnl4a txnl4a atp9b atp9b zgc:101562 zgc:101562 ctbp1 ctbp1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
znf516Zinc finger protein 516. (1084 aa)    
Predicted Functional Partners:
SLC66A2
Solute carrier family 66 member 2.
      
 0.837
rbfa
Ribosome-binding factor A.
    
 
 0.822
hsbp1l1
Uncharacterized protein.
      
 0.807
ice2
Interactor of little elongator complex ELL subunit 2.
    
 
 0.806
kdm1a
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 
 0.752
MAP3K13
Mitogen-activated protein kinase kinase kinase.
   
  
 0.749
txnl4a
Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.
      
 0.749
atp9b
Probable phospholipid-transporting ATPase IIB; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
   
 
 0.747
zgc:101562
Zgc:101562.
   
 
 0.698
ctbp1
C-terminal-binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.684
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.