STRINGSTRING
oprd1a oprd1a pomca pomca penka penka penkb penkb phactr4a phactr4a phactr4a-2 phactr4a-2 znf131 znf131 pdyn pdyn pomcb pomcb pnoca pnoca gmeb1 gmeb1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oprd1aOpioid receptor, delta 1a; Belongs to the G-protein coupled receptor 1 family. (374 aa)    
Predicted Functional Partners:
pomca
Pro-opiomelanocortin protein.
   
 0.929
penka
Proenkephalin a.
    
 0.901
penkb
Proenkephalin b.
   
 
 0.819
phactr4a
Phosphatase and actin regulator 4A.
   
  
 0.811
phactr4a-2
Phosphatase and actin regulator 4A; Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway (By similarity).
      
 0.807
znf131
Zinc finger protein 131.
      
 0.751
pdyn
Prodynorphin.
   
 
 0.730
pomcb
Proopiomelanocortin b.
   
  0.696
pnoca
Prepronociceptin a.
    
 0.640
gmeb1
Glucocorticoid modulatory element-binding protein 1.
      
 0.624
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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