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SDF4 SDF4 CALB1 CALB1 PVALB PVALB CALB2 CALB2 CALM2 CALM2 CALML3 CALML3 CALML4 CALML4 S100B S100B S100A4 S100A4 ENSGALP00000069842 ENSGALP00000069842 TRPV6 TRPV6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDF445 kDa calcium-binding protein; May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment; Belongs to the CREC family. (356 aa)    
Predicted Functional Partners:
CALB1
Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
      
 0.880
PVALB
Parvalbumin, muscle; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity); Belongs to the parvalbumin family.
      
 0.868
CALB2
Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons.
      
 0.862
CALM2
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
   
  
 0.744
CALML3
Calmodulin, striated muscle; Belongs to the calmodulin family.
      
 0.740
CALML4
Uncharacterized protein.
      
 0.715
S100B
EF-hand domain-containing protein; Belongs to the S-100 family.
      
 0.689
S100A4
EF-hand domain-containing protein.
    
 
 0.536
ENSGALP00000069842
Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.
      
 0.535
TRPV6
ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.533
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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