node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BTAF1 | DR1 | ENSGALP00000046624 | ENSGALP00000009403 | B-TFIID TATA-box binding protein associated factor 1. | Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). | 0.900 |
BTAF1 | DRAP1 | ENSGALP00000046624 | ENSGALP00000069114 | B-TFIID TATA-box binding protein associated factor 1. | DR1 associated protein 1. | 0.970 |
BTAF1 | TBP | ENSGALP00000046624 | ENSGALP00000060826 | B-TFIID TATA-box binding protein associated factor 1. | TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. | 0.938 |
BTAF1 | TBPL2 | ENSGALP00000046624 | ENSGALP00000019812 | B-TFIID TATA-box binding protein associated factor 1. | TATA box binding protein-like 2. | 0.927 |
DR1 | BTAF1 | ENSGALP00000009403 | ENSGALP00000046624 | Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). | B-TFIID TATA-box binding protein associated factor 1. | 0.900 |
DR1 | DRAP1 | ENSGALP00000009403 | ENSGALP00000069114 | Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). | DR1 associated protein 1. | 0.997 |
DR1 | KAT14 | ENSGALP00000009403 | ENSGALP00000014153 | Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). | N-acetyltransferase domain-containing protein. | 0.807 |
DR1 | POLE3 | ENSGALP00000009403 | ENSGALP00000039553 | Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). | CBFD_NFYB_HMF domain-containing protein. | 0.924 |
DR1 | SGF29 | ENSGALP00000009403 | ENSGALP00000037055 | Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). | SAGA-associated factor 29; Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me. | 0.802 |
DR1 | TADA2A | ENSGALP00000009403 | ENSGALP00000008736 | Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). | Transcriptional adapter 2-alpha; Component of some complex with histone acetyltransferase activity. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling (By similarity). | 0.876 |
DR1 | TADA3 | ENSGALP00000009403 | ENSGALP00000055576 | Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). | Transcriptional adaptor 3. | 0.795 |
DR1 | TBP | ENSGALP00000009403 | ENSGALP00000060826 | Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). | TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. | 0.908 |
DR1 | TBPL2 | ENSGALP00000009403 | ENSGALP00000019812 | Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). | TATA box binding protein-like 2. | 0.905 |
DR1 | YEATS2 | ENSGALP00000009403 | ENSGALP00000067137 | Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). | YEATS domain containing 2. | 0.810 |
DRAP1 | BTAF1 | ENSGALP00000069114 | ENSGALP00000046624 | DR1 associated protein 1. | B-TFIID TATA-box binding protein associated factor 1. | 0.970 |
DRAP1 | DR1 | ENSGALP00000069114 | ENSGALP00000009403 | DR1 associated protein 1. | Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). | 0.997 |
DRAP1 | TBP | ENSGALP00000069114 | ENSGALP00000060826 | DR1 associated protein 1. | TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. | 0.918 |
DRAP1 | TBPL2 | ENSGALP00000069114 | ENSGALP00000019812 | DR1 associated protein 1. | TATA box binding protein-like 2. | 0.918 |
KAT14 | DR1 | ENSGALP00000014153 | ENSGALP00000009403 | N-acetyltransferase domain-containing protein. | Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). | 0.807 |
KAT14 | POLE3 | ENSGALP00000014153 | ENSGALP00000039553 | N-acetyltransferase domain-containing protein. | CBFD_NFYB_HMF domain-containing protein. | 0.598 |