STRINGSTRING
UPRT UPRT UCK1 UCK1 UCK2 UCK2 PNP PNP LOC776992 LOC776992 UCKL1 UCKL1 UMPS UMPS DPYD DPYD CMPK2 CMPK2 CMPK1 CMPK1 UPP2 UPP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
UPRTUracil phosphoribosyltransferase homolog. (277 aa)    
Predicted Functional Partners:
UCK1
Uridine-cytidine kinase; Belongs to the uridine kinase family.
 
 0.999
UCK2
Uridine-cytidine kinase; Belongs to the uridine kinase family.
 
 0.998
PNP
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.988
LOC776992
Uridine-cytidine kinase; Belongs to the uridine kinase family.
 
0.986
UCKL1
Uridine-cytidine kinase; Belongs to the uridine kinase family.
  
0.986
UMPS
OMPdecase domain-containing protein.
    
 0.963
DPYD
Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.
   
 
 0.953
CMPK2
Cytidine/uridine monophosphate kinase 2.
    
 0.952
CMPK1
UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
  
 
 0.951
UPP2
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
     
 0.951
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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