STRINGSTRING
XRN2 XRN2 XRN1 XRN1 SETX SETX SKIV2L2 SKIV2L2 TENT2 TENT2 DROSHA DROSHA CDKN2AIP CDKN2AIP RPRD1B RPRD1B FBF1 FBF1 RPRD1A RPRD1A ENSGALP00000069104 ENSGALP00000069104
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
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[Homology]
Score
XRN25'-3' exoribonuclease 2; Possesses 5'->3' exoribonuclease activity. May promote the termination of transcription by RNA polymerase II (By similarity). Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily. (949 aa)    
Predicted Functional Partners:
XRN1
5'-3' exoribonuclease 1.
  
0.979
SETX
Senataxin.
   
 
 0.945
SKIV2L2
Uncharacterized protein.
   
 
 0.861
TENT2
Terminal nucleotidyltransferase 2.
   
  
 0.787
DROSHA
Uncharacterized protein.
   
 
 0.759
CDKN2AIP
CDKN2A interacting protein.
    
 
 0.735
RPRD1B
Cell-cycle related and expression-elevated protein in tumor.
   
 
 0.715
FBF1
Fas-binding factor 1 homolog; Keratin-binding protein required for epithelial cell polarization. Required for ciliogenesis (By similarity).
   
 
 0.712
RPRD1A
Regulation of nuclear pre-mRNA domain-containing protein 1A; Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle; Belongs to the UPF0400 (RTT103) family.
   
 
 0.712
ENSGALP00000069104
CID domain-containing protein.
   
 
 0.712
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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