NR1H4 protein (Gallus gallus) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

NR1H4

Farnesoid X receptor. (473 aa)

Predicted Functional Partners:

CYP7A1

0.930

PPARGC1A

0.917

NR0B2

0.899

RXRA

0.876

NCOA1

0.825

NCOA2

0.824

NCOR2

0.789

FABP6

0.762

MED1

0.736

RXRG

0.731

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP7A1	FABP6	ENSGALP00000054104	ENSGALP00000002196	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	FABP domain-containing protein.	0.432
CYP7A1	NR0B2	ENSGALP00000054104	ENSGALP00000001299	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	NR LBD domain-containing protein.	0.819
CYP7A1	NR1H4	ENSGALP00000054104	ENSGALP00000018906	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	Farnesoid X receptor.	0.930
FABP6	CYP7A1	ENSGALP00000002196	ENSGALP00000054104	FABP domain-containing protein.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.432
FABP6	NCOA1	ENSGALP00000002196	ENSGALP00000050346	FABP domain-containing protein.	Nuclear receptor coactivator.	0.507
FABP6	NCOA2	ENSGALP00000002196	ENSGALP00000053171	FABP domain-containing protein.	Nuclear receptor coactivator.	0.505
FABP6	NR0B2	ENSGALP00000002196	ENSGALP00000001299	FABP domain-containing protein.	NR LBD domain-containing protein.	0.449
FABP6	NR1H4	ENSGALP00000002196	ENSGALP00000018906	FABP domain-containing protein.	Farnesoid X receptor.	0.762
FABP6	RXRA	ENSGALP00000002196	ENSGALP00000046810	FABP domain-containing protein.	Retinoid X receptor alpha.	0.512
MED1	NCOA1	ENSGALP00000002620	ENSGALP00000050346	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor coactivator.	0.489
MED1	NCOA2	ENSGALP00000002620	ENSGALP00000053171	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor coactivator.	0.525
MED1	NCOR2	ENSGALP00000002620	ENSGALP00000073350	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor corepressor 2.	0.564
MED1	NR0B2	ENSGALP00000002620	ENSGALP00000001299	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	NR LBD domain-containing protein.	0.575
MED1	NR1H4	ENSGALP00000002620	ENSGALP00000018906	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Farnesoid X receptor.	0.736
MED1	RXRA	ENSGALP00000002620	ENSGALP00000046810	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoid X receptor alpha.	0.764
MED1	RXRG	ENSGALP00000002620	ENSGALP00000068361	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity).	0.763
NCOA1	FABP6	ENSGALP00000050346	ENSGALP00000002196	Nuclear receptor coactivator.	FABP domain-containing protein.	0.507
NCOA1	MED1	ENSGALP00000050346	ENSGALP00000002620	Nuclear receptor coactivator.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.489
NCOA1	NCOA2	ENSGALP00000050346	ENSGALP00000053171	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.855
NCOA1	NCOR2	ENSGALP00000050346	ENSGALP00000073350	Nuclear receptor coactivator.	Nuclear receptor corepressor 2.	0.786