node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEBP2 | EED | ENSGALP00000054126 | ENSGALP00000057840 | AE binding protein 2. | Polycomb protein EED; Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity). | 0.995 |
AEBP2 | EZH1 | ENSGALP00000054126 | ENSGALP00000056397 | AE binding protein 2. | Enhancer of zeste 1 polycomb repressive complex 2 subunit. | 0.971 |
AEBP2 | EZH2 | ENSGALP00000054126 | ENSGALP00000054289 | AE binding protein 2. | Enhancer of zeste 2 polycomb repressive complex 2 subunit. | 0.970 |
AEBP2 | JARID2 | ENSGALP00000054126 | ENSGALP00000020711 | AE binding protein 2. | Protein Jumonji; Regulator of histone methyltransferase complexes that plays an essential role in embryonic development. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone [...] | 0.998 |
AEBP2 | MTF2 | ENSGALP00000054126 | ENSGALP00000047838 | AE binding protein 2. | PHD-type domain-containing protein. | 0.768 |
AEBP2 | PHF19 | ENSGALP00000054126 | ENSGALP00000002418 | AE binding protein 2. | PHD finger protein 19. | 0.859 |
AEBP2 | RBBP4 | ENSGALP00000054126 | ENSGALP00000005565 | AE binding protein 2. | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. | 0.984 |
AEBP2 | RBBP7 | ENSGALP00000054126 | ENSGALP00000026647 | AE binding protein 2. | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. | 0.952 |
ATP5O | ATP6 | ENSGALP00000048855 | ENSGALP00000057531 | Uncharacterized protein. | ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] | 0.999 |
ATP5O | JARID2 | ENSGALP00000048855 | ENSGALP00000020711 | Uncharacterized protein. | Protein Jumonji; Regulator of histone methyltransferase complexes that plays an essential role in embryonic development. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone [...] | 0.874 |
ATP6 | ATP5O | ENSGALP00000057531 | ENSGALP00000048855 | ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] | Uncharacterized protein. | 0.999 |
ATP6 | JARID2 | ENSGALP00000057531 | ENSGALP00000020711 | ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] | Protein Jumonji; Regulator of histone methyltransferase complexes that plays an essential role in embryonic development. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone [...] | 0.874 |
EED | AEBP2 | ENSGALP00000057840 | ENSGALP00000054126 | Polycomb protein EED; Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity). | AE binding protein 2. | 0.995 |
EED | EZH1 | ENSGALP00000057840 | ENSGALP00000056397 | Polycomb protein EED; Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity). | Enhancer of zeste 1 polycomb repressive complex 2 subunit. | 0.993 |
EED | EZH2 | ENSGALP00000057840 | ENSGALP00000054289 | Polycomb protein EED; Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity). | Enhancer of zeste 2 polycomb repressive complex 2 subunit. | 0.999 |
EED | JARID2 | ENSGALP00000057840 | ENSGALP00000020711 | Polycomb protein EED; Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity). | Protein Jumonji; Regulator of histone methyltransferase complexes that plays an essential role in embryonic development. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone [...] | 0.995 |
EED | MTF2 | ENSGALP00000057840 | ENSGALP00000047838 | Polycomb protein EED; Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity). | PHD-type domain-containing protein. | 0.889 |
EED | PHF19 | ENSGALP00000057840 | ENSGALP00000002418 | Polycomb protein EED; Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity). | PHD finger protein 19. | 0.908 |
EED | RBBP4 | ENSGALP00000057840 | ENSGALP00000005565 | Polycomb protein EED; Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity). | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. | 0.996 |
EED | RBBP7 | ENSGALP00000057840 | ENSGALP00000026647 | Polycomb protein EED; Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity). | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. | 0.986 |