STRINGSTRING
ING4 ING4 BRD1 BRD1 JADE1 JADE1 BRPF1 BRPF1 BRPF3 BRPF3 MEAF6 MEAF6 ARID4A ARID4A ARID4B ARID4B TRRAP TRRAP KAT6A KAT6A KAT6B KAT6B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ING4Inhibitor of growth protein 4; Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation (By similarity); Belongs to the ING family. (249 aa)    
Predicted Functional Partners:
BRD1
Uncharacterized protein.
    
 0.891
JADE1
Jade family PHD finger 1.
    
 
 0.883
BRPF1
Uncharacterized protein.
    
 0.833
BRPF3
Bromodomain and PHD finger containing 3.
    
 0.830
MEAF6
Chromatin modification-related protein MEAF6; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vi [...]
   
 0.817
ARID4A
ARID domain-containing protein.
   
 
 0.654
ARID4B
AT-rich interaction domain 4B.
   
 
 0.650
TRRAP
Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.
   
 
 0.600
KAT6A
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
   
 0.592
KAT6B
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.592
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (6%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.